NMR Enhancement with Gd Labeled Antibodies
With the development of monoclonal antibodies, the hope of a magic bullet has been revived. Many therapeutic and diagnostic agents have been linked to monoclonal antibodies in order to add specificity to the process. Few of these combinations have reached their clinical potential. One such proposal deals with the combination of an antibody with a new image enhancing agent, a paramagnetic compound, for use with nuclear magnetic resonance (NMR) imaging. There are a number of ways that a diagnostic image can be enhanced by a chemical (Table 1).
KeywordsBifunctional Chelate 99mTc DTPA Paramagnetic Substance Polyglutamic Acid Paramagnetic Compound
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