Radioimmunoscintigraphy — SPECT with I-131 — MAbs; Comparison with TCT in the Follow-up of Colorectal Cancer
At the Department of Radiology of the University of Munich, a clinical trial was started about two years ago in order to evaluate the diagnostic applications of radiolabeled monoclonal antibodies (MAbs). A main emphasis is the malignant melanoma of the skin, and the eye melanoma, using Tc-99m labeled anti-melanoma antibody 225.28S developed by Ferrone (1). In addition, several MAbs, mainly labeled with I-131, were investigated in patients with gastrointestinal cancer. This paper presents a part of the results of radioimmunoscintigraphy (RIS) using single photon emission computed tomography (SPECT) in a very selected group of patients with sigmoidal or rectal cancer.
KeywordsRectal Cancer Urinary Bladder Serum Tumor Marker True Positive Result Metastatic Ovarian Tumor
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