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Antibody — Carboxypeptidase G2 Conjugates as Potential Tumour Imaging Agents

  • Conference paper
Radiolabeled Monoclonal Antibodies for Imaging and Therapy

Part of the book series: NATO ASI Series ((NSSA,volume 152))

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Abstract

Although monoclonal antibodies (Moab) are useful for delineating small residual deposits of tumor, radioimmunolocalization (RIL) in humans would be greatly improved if nonlocalizing antibody was removed from the blood pool more effectively, and uptake of antibody in other tissues, particularly by hepatic Fc receptors, was reduced.

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Author information

Authors and Affiliations

  1. Microbial Technology Laboratory, PHLS Centre for Applied Microbiology and Research, Porton Down, Salisbury, UK

    R. G. Melton & R. F. Sherwood

  2. Department of Medical Oncology, Charing Cross Hospital, London, UK

    F. Searle, C. Bier, J. A. Boden, R. B. Pedley, A. J. Green & K. D. Bagshawe

Authors
  1. R. G. Melton
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  2. F. Searle
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  3. C. Bier
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  4. J. A. Boden
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  5. R. B. Pedley
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  6. A. J. Green
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  7. K. D. Bagshawe
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  8. R. F. Sherwood
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Editor information

Editors and Affiliations

  1. Brookhaven National Laboratory, Upton, New York, USA

    Suresh C. Srivastava

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© 1988 Springer Science+Business Media New York

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Melton, R.G. et al. (1988). Antibody — Carboxypeptidase G2 Conjugates as Potential Tumour Imaging Agents. In: Srivastava, S.C. (eds) Radiolabeled Monoclonal Antibodies for Imaging and Therapy. NATO ASI Series, vol 152. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5538-0_26

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  • DOI: https://doi.org/10.1007/978-1-4684-5538-0_26

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-5540-3

  • Online ISBN: 978-1-4684-5538-0

  • eBook Packages: Springer Book Archive

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