Quantification and Class Distribution of Immunoglobulin-Secreting Cells in Mucosal Tissues of the Chicken

  • G. Koch
  • I. M. C. A. Jongenelen
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 237)


Immunoglobulin-secreting cells (Ig-SC) can be observed in animals that are not deliberately immunized. This phenomenon has been referred to as spontaneous “background” Ig production (1). The background Ig production is induced both by endogenous and exogenous antigenic stimuli(2,3,4). Exogenous stimuli mainly depend on antigens that cross the mucosae. Therefore, studying the development of the spontanous Ig-SC response at mucosal sites is an appropriate way to acquire more insight into the functioning of the mucosal immune system in chickens.


Class Distribution Mucosal Immune System Mucosal Site Harderian Gland Caecal Tonsil 
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Copyright information

© Plenum Press, New York 1988

Authors and Affiliations

  • G. Koch
    • 1
  • I. M. C. A. Jongenelen
    • 1
  1. 1.Dept. of VirologyCentral Veterinary InstituteLelystadThe Netherlands

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