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Migration Patterns of Dendritic cells in the Mouse

  • J. M. Austyn
  • J. W. Kupiec-Weglinski
  • P. J. Morris
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 237)

Abstract

Dendritic cells (DC) in lymphoid organs and related cells in non-lymphoid tissues play a pivotal role in the induction of T lymphocyte responses (reviewed in Austyn, 1987). DC stimulate primary immune responses in culture and in vivo, and trigger allograft rejection. However, their mode of entry to the tissues and subsequent fate, and the significance of apparently mature DC in blood is unclear.

Keywords

Marginal Zone Mature Dendritic Cell High Endothelial Venule Interdigitating Cell Splenic Dendritic Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Austyn JM. (1983) Lymphoid dendritic cells. Immunology. 62: 161–170.Google Scholar
  2. Austyn JM, Kupiec-Weglinski JW, Hankins DP and Morris PJ. (1988) Migration patterns of dendritic cells in the mouse. Homing to T-cell-dependent areas of spleen, and binding within marginal zone. J. Exp. Med. In press.Google Scholar
  3. Kupiec-Weglinski JW, Austyn JM and Morris PJ. (1988) Migration patterns of dendritic cells in the mouse. Traffic from the blood, and T-cell-dependent and — independent entry to lymphoid tissues. J. Exp. Med. In press.Google Scholar

Copyright information

© Plenum Press, New York 1988

Authors and Affiliations

  • J. M. Austyn
    • 1
  • J. W. Kupiec-Weglinski
    • 1
  • P. J. Morris
    • 1
  1. 1.Nuffield Department of SurgeryUniversity of Oxford John Radcliffe HospitalOxfordUSA

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