MEL-14 and LFA-1, Organ Specific and Non-Specific Adhesion Molecules Involved in Homing of Human Lymphocytes
In the process of recirculation lymphocytes migrate from the blood into the surrounding tissues by adhering to and crossing the wall of high endothelial venules (1–4). Recently we and others have provided evidence that in man, like in rodents, a system of organ-specific receptors mediates lymphocyte-HEV recognition and thus presumably controls lymphocyte homing to lymphoid tissues and sites of inflammation (4–7).
KeywordsHuman Lymphocyte Peripheral Lymph Node High Endothelial Venule Significant Additive Effect Lymphocyte Recirculation
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