Changes in Lymphocyte Binding and Expression of his 22 of High Endothelial Venules in Rat Lymph Nodes after Occlusion of Afferent Lymph Flow

  • H. R. Hendriks
  • C. Korn
  • A. M. Duijvestijn
  • G. Kraal
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 237)


Recirculating lymphocytes migrate from the blood into lymph nodes through the walls of the high endothelial venules (HEV). HEV are lined by large plump so-called high endothelial cells (HE cells) to which lymphocytes specifically adhere. This specific interaction can be studied in vitro by overlaying lymphocyte suspensions on cryostat sections of lymph nodes (1-3).


Lymph Node Cryostat Section Normal Lymph Node Popliteal Lymph Node High Endothelial Venule 
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Copyright information

© Plenum Press, New York 1988

Authors and Affiliations

  • H. R. Hendriks
    • 1
  • C. Korn
    • 1
  • A. M. Duijvestijn
    • 2
  • G. Kraal
    • 1
  1. 1.Dept. Cell Biology, Medical FacultyFree UniversityAmsterdamThe Netherlands
  2. 2.Dept. HistologyState University GroingenThe Netherlands

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