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Expression and Regulation of an Antigen Specific for Endothelium Involved in Human Lymphocyte Homing

  • Eveliene Horst
  • Steven T. Pals
  • Ad M. Duijvestijn
  • Jan v. Mourik
  • Georg Kraal
  • Eugene C. Butcher
  • Chris J. L. M. Meijer
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 237)

Abstract

Lymphocyte migration from blood to lymph is mediated by high endothelial venules (HEV), a specialized class of postcapillary venules characterized by plump or “high ” endothelial morphology (1,2,3). HEV are normally present in the paracortex of lymph nodes and mucosa associated lymphoid tissues, moreover vessels with HEV-like morphology can arise at sites of inflammation (4,5).

Keywords

Grave Disease Lichen Planus Mucosa Associate Lymphoid Tissue Autoimmune Thyroiditis High Endothelial Venule 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1988

Authors and Affiliations

  • Eveliene Horst
    • 1
  • Steven T. Pals
    • 1
  • Ad M. Duijvestijn
    • 3
  • Jan v. Mourik
    • 4
  • Georg Kraal
    • 2
  • Eugene C. Butcher
    • 5
  • Chris J. L. M. Meijer
    • 1
  1. 1.Dept. of PathologyFree UniversityAmsterdamThe Netherlands
  2. 2.Dept. of HistologyFree UniversityAmsterdamThe Netherlands
  3. 3.Dept. of HistologyState UniversityGroningenThe Netherlands
  4. 4.Dept. of Blood CoagulationC.L.B.AmsterdamThe Netherlands
  5. 5.Dept. of PathologyStanford School of MedicineStanfordUSA

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