B Cell Precursor Populations in Fetal and Neonatal Rat Liver: Frequency, Topography and Antigenic Phenotype
In rodents and man B lymphocyte development starts in fetal liver, and gradually shifts to the bone marrow where it is maintained throughout life (1). The immediate precursors of newly formed surface IgM bearing B cells are pre-B cells defined by the presence of μ heavy chains (but not light chains) in the cytoplasm only (1).
KeywordsFetal Liver Adult Bone Marrow Fetal Liver Cell Neonatal Liver Precursor Population
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