Pattern of Distribution of Early B Lineage Cells in Rat Bone Marrow

  • Mirjam Hermans
  • Hans Hartsuiker
  • Davine Opstelten
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 237)


In mammals bone marrow (BM) is the primary site of B lymphocyte genesis in postnatal life, providing precursors for antibody forming cells for humoral immune responses. The B progenitor cells are situated in the BM within a three dimensional network formed by stromal cells, vascular elements and erythroid, myeloid and lymphoid cells. Little is known about their spatial organisation.


Goat Anti Mouse Bone Marrow Section Sinus Lumen Bone Marrow Endothelium Mammal Bone Marrow 
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Copyright information

© Plenum Press, New York 1988

Authors and Affiliations

  • Mirjam Hermans
  • Hans Hartsuiker
  • Davine Opstelten
    • 1
  1. 1.Department of HistologyUniversity of GroningenGroningenthe Netherlands

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