Pattern of Distribution of Early B Lineage Cells in Rat Bone Marrow
In mammals bone marrow (BM) is the primary site of B lymphocyte genesis in postnatal life, providing precursors for antibody forming cells for humoral immune responses. The B progenitor cells are situated in the BM within a three dimensional network formed by stromal cells, vascular elements and erythroid, myeloid and lymphoid cells. Little is known about their spatial organisation.
KeywordsGoat Anti Mouse Bone Marrow Section Sinus Lumen Bone Marrow Endothelium Mammal Bone Marrow
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- 6.S.V. Hunt, E.S. Medlock, D.L. Greiner, I. Goldschneider, and D. Opstelten. Rat immunoglobulin genes have comparable patterns of JH rearrangements in normal peripheral B cells and in pre-B and cultured TdT+ cells from bone marrow. This volume.Google Scholar
- 9.F.G.M. Kroese, A.S. Wubbena, D. Opstelten, G.J. Deenen, E.H. Schwander, L. de Leij, H. Vos, S. Poppema, J. Volberda, and P. Nieuwenhuis. B lymphocyte differentiation in the rat: production and characterization of monoclonal antibodies to B lineage associated antigens. Eur. J. Immunol. 17: 921 (1987).PubMedCrossRefGoogle Scholar