A Low Density Fraction of Bone Marrow Cells Enriched in Prothymocyte Activity

  • S. Ezine
  • B. Nabarra
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 237)


The very early steps of T cell differentiation are not yet well understood. Many difficulties can be reported: 1/ the lack of surface markers on very immature population (prothymocytes and their direct progeny) and 2/ the absence of informations about the inductive signals involved in triggering the precursor subset.


Bone Marrow Cell Ficoll Gradient Donor Type Cell Total Bone Marrow Cell Type Bone Marrow 
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  1. 1.
    Kadish, J.L. and R.S. Basch (1976) J. Exp. Med. 143, 1082.PubMedCrossRefGoogle Scholar
  2. 2.
    El Arini, M.O. and Osoba, D. (1973). J. Exp. Med. 137, 821.PubMedCrossRefGoogle Scholar
  3. 3.
    Coffman, R. (1982). Immunol. Rev. 69, 5.PubMedCrossRefGoogle Scholar
  4. 4.
    Dialynas, D.P. et al. (1983). Immunol. Rev. 74, 29.PubMedCrossRefGoogle Scholar
  5. 5.
    Tak Yan DU, D. et al. (1973). J. Immunol. 110, 151.Google Scholar
  6. 6.
    Papiernk, M. and Bach J.F. (1977). Eur. J. Immunol. 7, 800.CrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1988

Authors and Affiliations

  • S. Ezine
    • 1
  • B. Nabarra
    • 1
  1. 1.INSERM U25 — Hôpital Necker75743 ParisFrance

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