Thymic Stromal Elements Defined by M.Abs: Ontogeny, and Modulation in Vivo By Immunosuppression
The complex intra-thymic processes culminating in the generation of fully functional, self tolerant, self MHC restricted T lymphocytes have proven difficult to decipher. They appear to involve extensive interactions between T cell progenitors and thymic stromal cells or their soluble products. A better understanding of these mechanisms, however, has been hampered through the inability to identify and isolate individual sub-populations from the extremely heterogeneous thymic stroma.
KeywordsStromal Cell Stromal Element Mouse Thymus Thymic Lymphocyte Thymic Stromal Cell
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