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Thymic Stromal Elements Defined by M.Abs: Ontogeny, and Modulation in Vivo By Immunosuppression

  • D. I. Godfrey
  • D. J. Izon
  • T. J. Wilson
  • C. L. Tuček
  • R. L. Boyd
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 237)

Abstract

The complex intra-thymic processes culminating in the generation of fully functional, self tolerant, self MHC restricted T lymphocytes have proven difficult to decipher. They appear to involve extensive interactions between T cell progenitors and thymic stromal cells or their soluble products. A better understanding of these mechanisms, however, has been hampered through the inability to identify and isolate individual sub-populations from the extremely heterogeneous thymic stroma.

Keywords

Stromal Cell Stromal Element Mouse Thymus Thymic Lymphocyte Thymic Stromal Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1988

Authors and Affiliations

  • D. I. Godfrey
    • 1
  • D. J. Izon
    • 1
  • T. J. Wilson
    • 1
  • C. L. Tuček
    • 1
  • R. L. Boyd
    • 1
  1. 1.Department of Pathology and ImmunologyMonash UniversityMelbourneAustralia

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