Skip to main content

Morphologicl Diversity of DRC-1 Pospitive Cells: Human Follicular Dendritic Cells and their Relatives

  • Chapter
Histophysiology of the Immune System

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 237))

Abstract

Follicular dendritic cells (FDC) have been regarded as antigen-trapping cells playing roles in immune amplification especially in the secondary reponse.4,7,9) However their morphological spectrum has not been enough -clarified since their cytoplasmic extensions are too complicatedly interwoven to observe in banal electron microsopy. The purpose of this report is to analyze their morphological profile and spectrum of human FDC with a monoclonal antibody DRC-l(DAKO)2) specific to FDC and their relatives, in a combination with an isolation technique of FDC according to Tew et al.6)

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Dobashi, M, Terashima K et lirai Y: Postnatal development of dendrtic reticulum cells and their immune complex trapping ability. Histol. Histopath. 1, 19, 1986

    Google Scholar 

  2. Gerdes, J., Naiem, M., Mason, D.Y. and Stein, H.: Human complement (C3b) receptors defined by a mouse monoclonal antibody. Inmunology, 45, 45, 1982

    Google Scholar 

  3. Heinen, E., Lilet-Leclercq, Ch., Mason, DY., Stein, H., Boniever, J. et al.: Isolation of follicular dendritic cells from human tonsils and adenoids. II Immunocytochemicl characterizatioln. Eur. J. Immunol. 14, 267–273, 1984.

    Article  PubMed  CAS  Google Scholar 

  4. Imai, Y., Terashima, K., Matsuda, M., Dobashi, M., Maeda, K. et Kasajima T.: Reticulum cell and dendritic cells-origin and function Rec. Adv. RES. 21, 51, 1983

    Google Scholar 

  5. Parwaresch, M.R., Radzun, H.J., Hanmann, M.L. et Peters, K.P.: Monoclonal antibody Ki-M4 specifically recognizes human dendritic eells (follicular dendritic clls) and their possible precursors in blood. Blood, 72, 585, 1985

    Google Scholar 

  6. Schnizlen, C.T., Kosco, MH., Szakal, AK. et Tew, JG.:Follicuar dendritic cells in suspension enrichment, and initial characterization indicating immune complex trapping and lack of adherence and phagocytic activity. J. Immunol. 134, 1360, 1985

    Google Scholar 

  7. Terashima, K., Imai, Y., Kasajima, T., Tsunoda, R., Takahashi, K. et Kojima, M.: An ultrastructural study on antibody roduction of the lymph nodes of rats with special reference to the role of germinal centers. Acta Pathol. Jpn, 27, 1, 1977

    PubMed  CAS  Google Scholar 

  8. Terashima, K., Ukai, K. et lirai Y: Heterogenity of DRC-1 positve cells in Abstract n24 in international conference of “Antigen Presenting Cells-Diversity, differentiation and regulation” Richmond Virginia, USA 1987

    Google Scholar 

  9. Tew, JG: Role of follicular dendritic cells in the “alternative antigen pathway leading from irrmune complex formation to antigen presentation by germinal center B cells, in Abstract n2 in International Conference of “Antigen Presenting Cells-Diversity,differtiation and regulation” in Richmond, Virginia, USA, 1987

    Google Scholar 

  10. Humphery, JH, Grennan, D. and Sundaram, V.: The origin of follicular dendrritic cells in the mouse and the mechanism of trapping of irrmune complex. Eur. J. Irrmunol. 14, 854–864, 1984.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1988 Plenum Press, New York

About this chapter

Cite this chapter

Terashma, K., Ukai, K., Tajima, K., Yuda, F., Imai, Y. (1988). Morphologicl Diversity of DRC-1 Pospitive Cells: Human Follicular Dendritic Cells and their Relatives. In: Fossum, S., Rolstad, B. (eds) Histophysiology of the Immune System. Advances in Experimental Medicine and Biology, vol 237. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5535-9_22

Download citation

  • DOI: https://doi.org/10.1007/978-1-4684-5535-9_22

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-5537-3

  • Online ISBN: 978-1-4684-5535-9

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics