Physical Interaction Between Dendritic Cells and Lymphocytes is not LFA-1 Mediated

  • Eliane Buss
  • Heinz-Günter Thiele
  • Alf Hamann
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 237)


Dendritic cells from spleen, lymph nodes and other organs have been found to represent the most efficient accessory cell population for the induction of a primary immune response. Interaction with lymphocytes is thought to take place via direct cell-cell contact and indeed a striking property of dendritic cells is their ability to form clusters with lymphocytes containing that T-cell fraction becoming activated subsequently (1).


Dendritic Cell Accessory Cell Primary Immune Response Mixed Cluster Accessory Molecule 
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Copyright information

© Plenum Press, New York 1988

Authors and Affiliations

  • Eliane Buss
    • 1
  • Heinz-Günter Thiele
    • 1
  • Alf Hamann
    • 1
  1. 1.Abt. f. klin. Immunologie, I. Med. KlinikUniv. krankenhaus2 Hamburg 20Germany

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