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Phenotypic Changes in Cultured Rat Dendritic Cells: Expression of IL-2 Receptor, Thy-1 and Other Antigens

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Histophysiology of the Immune System

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 237))

Abstract

The lymphoid dendritic cell (DC) is thought, mainly as a result of ‘in vitro’ studies, to play a central role in the initiation of. immune responses, particularly in the activation of resting T lymphocytes (1). However, despite considerable investigation, relatively little is known of the ‘in vivo’ physiology and life history of the DC.

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References

  1. R.M. Steinman, K. Inaba, G. Schüler, and M. Witmer in “Mechanisms of host resistance to infectious agents, tumors and allografts”, p.71, R.M. Steinman and R.J. North, eds., The Rockefeller University Press, (1986).

    Google Scholar 

  2. R.M. Steinman, D.S. Lustig, and Z.A. Conn. J. Exp. Med. 139: 1431 (1974).

    Article  PubMed  CAS  Google Scholar 

  3. C.W. Pugh, G.G. MacPherson, and H,W. Steer. J. Exp. Med. 157: 1758 (1983).

    Article  PubMed  CAS  Google Scholar 

  4. D.N.J. Hart and J.W. Fahre. J. Exp. Med. 154: 347 (1981).

    Article  PubMed  CAS  Google Scholar 

  5. R.H. Kelly, B.M. Balfour, J.A. Armstrong, and S. Griffiths. Anat. Rec. 190: 5 (1978).

    Article  PubMed  CAS  Google Scholar 

  6. I. Silberberg-Sinakin, G.J. Thorbecke, R.L. Baer, S.A. Rosenthal, and V. Berezowsky. Cell. Immunol. 25: 137 (1976).

    Article  PubMed  CAS  Google Scholar 

  7. G. Schuler, and R.M. Steinman. J. Exp. Med. 161: 526 (1985).

    Article  PubMed  CAS  Google Scholar 

  8. G.G. MacPherson, and C.W. Pugh. Immunobiol. 168: 338 (1984).

    Article  CAS  Google Scholar 

  9. D.W. Mason. Transplant. 32: 222 (1981).

    Google Scholar 

  10. L. Hsiung, A.N. Barclay, M.R. Brandon, E. Sim, and R.R. Porter. Biochem. J. 203: 293 (1982).

    PubMed  CAS  Google Scholar 

  11. W.R. McMaster, and A.F. Williams. Immunol. Rev. 47: 117 (1979).

    Article  PubMed  CAS  Google Scholar 

  12. D.W. Mason, and A.F. Williams. Biochem. J. 187: 1 (1980).

    PubMed  CAS  Google Scholar 

  13. D.W. Mason, R.P. Arthur, M.J. Dallman, J.R. Green, G.P. Spickett, and M.L. Thomas. Immunol. Rev. 74: 57 (1983).

    Article  PubMed  CAS  Google Scholar 

  14. A.F. Williams, A.N. Barclay, S.J. Clark, D.J. Patterson, and A.C. Willis. J. Exp. Med. 165: 368 (1986).

    Article  Google Scholar 

  15. D.J. Patterson, W.A. Jefferies, J.R. Green, M.R. Brandon, P. Cortese, M. Puklavec, and A.F. Williams. Molec. Immunol. In press.

    Google Scholar 

  16. A.P. Robinson, T.M. White, and D.W. Mason. Immunol. 57: 239 (1986).

    CAS  Google Scholar 

  17. W.A Kuziel, A. Takashima, M. Bonyhadi, P.R. Bergstresser, J.P. Allison, R.E. Tigelaar, and P.W. Tucker. Nature. 328: 263 (1987).

    Article  PubMed  CAS  Google Scholar 

  18. F. Herman, S.A. Cannistra, H. Levine, and J.D. Griffin. J. Exp. Med. 162: 1111 (1985).

    Article  Google Scholar 

  19. G. Steiner, E. Tschachler, M. Tani, T.R. Malek, E.M. Shevach, W. Holter, W, Knapp, K. Wolff, and G. Stingl. J. Immunol. 137: 155 (1986).

    PubMed  CAS  Google Scholar 

  20. M. Kotani, T. Ezaki, H. Fuji, K. Matsuno, S. Ekino, and S. Harada. Acta. Anat. 104: 406 (1979).

    Article  PubMed  CAS  Google Scholar 

  21. G.J. Deenan, D. Opstelten, and P. Niewenhuis. Cell. Tiss. Res. 238: 183 (1984).

    Google Scholar 

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© 1988 Plenum Press, New York

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MacPherson, G.G. (1988). Phenotypic Changes in Cultured Rat Dendritic Cells: Expression of IL-2 Receptor, Thy-1 and Other Antigens. In: Fossum, S., Rolstad, B. (eds) Histophysiology of the Immune System. Advances in Experimental Medicine and Biology, vol 237. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5535-9_114

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  • DOI: https://doi.org/10.1007/978-1-4684-5535-9_114

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-5537-3

  • Online ISBN: 978-1-4684-5535-9

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