Differential Expression of Epithelial MHC Class II Determinants (HLA-DR, -DP, and -DQ) and Increased Class I Expression in Inflamed Salivary Glands
Sjögren’s syndrome (SS) affects salivary and lacrimal glands, causing xerostomia and keratoconjunivitis. An increased number of infiltrating leukocytes are present and the glandular tissue is gradually destroyed. Increased epithelial HLA-DR expression in salivary glands from SS patients has been reported (1,2,3), but the other MHC class II subregion products(HLA-DP and -DQ) and MHC class I determinants have not been studied.
KeywordsSalivary Gland Pleomorphic Adenoma Salivary Gland Tissue Salivary Gland Epithelial Cell Epithelial Expression
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