The EEG in the Determination of Brain Death in Pediatric Patients The NIH Study
The National Institute of Health Collaborative Study of Cerebral Survival (CS) remains the largest prospective study on the outcome of patients with cerebral unresponsivity and apnea. One purpose of this investigation was to formulate a set of criteria that would identify a dead brain in an otherwise living body. Although patients under 1 year of age were excluded and only 43 of the 503 patients enrolled were between the ages of 1 and 9 years, the electroencephalographic (EEG) results of this study are relevant to the pediatric brain-death issue. Therefore, the EEG experiences and findings are reviewed and correlated with clinical data as well as with other investigations. Where potential problems or differences in the pediatric age group are seen, they are so commented on. Since the CS report was published, it has been criticized, and some of the criticisms are justified, particularly the working definition of apnea. However, the CS study serves as a prototype for future investigations.
KeywordsSudden Infant Death Syndrome Pediatric Intensive Care Unit Brain Death Interelectrode Distance Brainstem Reflex
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