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The Immune System

  • Benjamin B. Wolman

Abstract

The immune system is a guardian apparatus that defends the living organism against foreign bodies and, especially, disease-causing microorganisms such as germs and viruses:
  • The principal cells of the immune system are lymphocytes, plasma cells, and macrophages which are parts of the lymphoid tissue. The thymus, lymph nodes and spleen are examples of highly developed lymphoid tissues. The gastrointestinal tract, the tonsils, the Peyer’s patches and the appendix also have lymphoid tissue. …

  • There are two distinct types of lymphocytes. These two types were first demonstrated in chickens by removal of the thymus or by removal of the bursa of Fabricius (a lymphoid organ near the cloaca) during the neonatal period. Excision of the bursa resulted in low immunoglobulin levels and impaired antibody synthesis. Lymphoid nodules did not develop in lymph nodes and spleen. … The cell-mediated immunity remained intact as proven by delayed hypersensitivity and allograft rejection. Evidence for two types of immunocompetent cells in humans has largely come from the study of congenital and acquired defects of immunity as well as from the identification of populations of lymphocytes. The two types of immunocompetent lymphocytes are referred to as B cells and T cells. (Gilliland, 1980, p. 315)

Keywords

Immune System Systemic Lupus Erythematosus Behavioral Medicine Infectious Mononucleosis Psychosomatic Disorder 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Ader, R. (Ed.). Psychoneuroimmunology. New York: Academic Press, 1981.Google Scholar
  2. Ader, R., & Cohen, N. Behavior and the immune system. In W. D. Gentry (Ed.), Handbook of behavioral medicine (pp. 117–173). New York, London: Guilford Press, 1984.Google Scholar
  3. Bartrop, R. W., Luckhurst, E., Lazarus, L., & Kiloh, L. G. Depressed lymphocyte function after bereavement. Lancet, 1977, 1, 834–836.PubMedCrossRefGoogle Scholar
  4. Bilick, H. A., & Nuland, W. A. Psychosocial model in the treatment of cancer patients. In J. G. Goldberg (Ed.), Psychotherapeutic treatment of cancer patients (pp. 58–70). New York: Free Press, 1981.Google Scholar
  5. Dorian, B. J., Keystone, E., Garfinkel, P. E., & Brown, G. M. Aberrations in lymphocytes subpopulations and functions during psychological stress. Clinical-Experimental Immunology, 1982, 50, 132–138.PubMedPubMedCentralGoogle Scholar
  6. Franz, M. L. von. Der Traum des Descartes. In C. A. Meyer (Ed.), Zeitlose Dokumente der Seele. Zurich: Rascher, 1952.Google Scholar
  7. Gilliland, B. C. Introduction to clinical immunology. In T. R. Harrison (Ed.), Principles of internal medicine (9th ed., pp. 315–325). New York: McGraw-Hill, 1980.Google Scholar
  8. Goldberg, J. G. (Ed.). Psychotherapeutic treatment of cancer patients. New York: Free Press, 1981.Google Scholar
  9. Jermott, J. B., & Locke, S. E. Psychosocial factors, immunologic meditation, and human susceptibility to infectious diseases. Psychological Bulletin, 1984, 95, 52–77.CrossRefGoogle Scholar
  10. Kimball, C. P. Diagnosing psychosomatic situations. In B. B. Wolman (Ed.), Clinical diagnosis of mental disorders: A handbook (pp. 677–708). New York: Plenum Press, 1978.CrossRefGoogle Scholar
  11. Levy, S. (Ed.). Biological mediator of stress and disease: Neoplasms. New York: Elsevier-North Holland, 1982.Google Scholar
  12. Lipowski, Z. J. Psychosomatic medicine and liason psychiatry. New York: Plenum Press, 1985.CrossRefGoogle Scholar
  13. Mason, J. W. Psychologic stress and endocrine function. In F. J. Sachar (Ed.), Topics in endocrinology. New York: Grune & Stratton, 1975.Google Scholar
  14. Miller, N. E. Behavioral medicine: Symbiosis between laboratory and clinic. Annual Review of Psychology, 1983, 34, 1–32.PubMedCrossRefGoogle Scholar
  15. Silverberg, E. Cancer statistics. New York: American Cancer Society, 1984.Google Scholar
  16. Simonton, O. C., & Simonton, S. Belief systems and management of the emotional aspects of malignancy. Journal of Transpersonal Psychology, 1975, 7, 29–47.Google Scholar
  17. Simonton, D. C., & Simonton, S. Getting well again. New York: Prentice-Hall, 1978.Google Scholar
  18. Solomon, G. E., & Amkraut, A. A. Psychoneuroendocrinological effects of the immune response. Annual Review of Microbiology, 1981, 35, 155–184PubMedCrossRefGoogle Scholar
  19. Stein, M., Schiavi, R., & Camerino, M. Influence of brain and behavior on the immune system. Science, 1976, 191, 435–440.PubMedCrossRefGoogle Scholar
  20. Stein, M., Schleifer, S. J., & Keller, S. E. Immune disorders. In H. I. Kaplan & B. J. Sadock (Eds.), Comprehensive textbook of psychiatry (4th ed.), pp. 1206–1212). Baltimore, Maryland: Williams & Wilkins, 1985.Google Scholar
  21. Zegans, L. S. Stress and the development of somatic disorders. In L. Goldberger & S. Bresnitz (Eds.), Handbook of stress (pp. 134–152). New York: Free Press, 1982.Google Scholar

Copyright information

© Plenum Publishing Corporation 1988

Authors and Affiliations

  • Benjamin B. Wolman

There are no affiliations available

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