Heterogeneity of Growth Hormone

  • Gerhard Baumann
Part of the Serono Symposia, USA book series (SERONOSYMP)


Heterogeneity of polypeptide hormones is a ubiquitous phenomenon related to gene multiplicity, biosynthetic precursors, aggregation, protein-protein interaction, fragment formation, differential glycosylation, derivatization of functional groups, degradative processes, and lack of complete assay specificity. Some of this heterogeneity occurs as a physiological process, and some represents a laboratory artifact. Growth hormone (GH) is no exception and its heterogeneity has been recognized for a long time, although the details have only recently become clear. This review will primarily deal with human GH (hGH), which is the best studied in terms of structure among the various animal GHs.


Growth Hormone Human Growth Hormone Pituitary Growth Hormone Growth Hormone Binding Growth Hormone Binding Protein 
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Copyright information

© Plenum Press, New York 1988

Authors and Affiliations

  • Gerhard Baumann
    • 1
  1. 1.Center for Endocrinology, Metabolism and Nutrition Department of MedicineNorthwestern University Medical SchoolChicagoUSA

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