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Developmental and Molecular Studies of Neurons that Express FMRFamide-Related Genes in Insects

  • Paul H. Taghert

Abstract

Ernst and Berta Scharrer first demonstrated the glandular nature of magnocellular neurons more than 40 years ago. Since that time considerable effort has been made to prove the neuronal nature of neurosecretory cells (NSC) in the mammalian hypothamalmus and elsewhere: it has been shown for example, that these cells have active membrane properties (Copenhaver and Truman, 1986), that they have complex neuronal geometries (Taghert and Truman, 1982), and that they receive varied neuronal synaptic inputs (Jansen and Bos, 1984). Perhaps the sole distinction that can still be drawn between NSCs and conventional neurons is that, while the latter contact and synapse upon discrete cellular elements, NSCs instead form “blind”, synaptoid endings within structures termed Neurohaemal Organs (NHO). It is from such NSC terminations that various neuropeptides are released into the circulation and eventually act on cellular targets that are microns to meters away.

Keywords

Growth Cone Neurosecretory Cell Segmental Ganglion Neurosecretory Neuron Active Membrane Property 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1988

Authors and Affiliations

  • Paul H. Taghert
    • 1
  1. 1.Department of Anatomy and NeurobiologyWashington University School of MedicineSaint LouisUSA

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