Neurosecretion pp 227-234 | Cite as

Intrinsic Electrophysiological Regulation of Firing Patterns of Bursting Neurons in Aplysia

  • Robert S. Zucker


Endogenous generation of action potential bursts occurs commonly among peptidergic neurosecretory cells (Barker and Gainer, 1975; Gähwiler and Dreilfuss, 1977; Cooke, 1982; Andrew and Dudek, 1984). Burst generation has also been observed in more typical central neurons (Miller and Selverston, 1982; Grace and Bunney, 1984; Legendre et al., 1985), indicating that it is a property of many kinds of neurons. It is easily imagined that burst generation functions to enhance transmitter release, which by synaptic facilitation may be particularly sensitive to spike frequency, but it has been difficult to prove this point (Dutton and Dyball, 1979). Bursting neurons have also been implicated in the organization of rhythmic motor patterns (Miller and Selverston, 1982).


Outward Current Burst Neuron Spike Burst Pacemaker Current Burst Generation 


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Copyright information

© Plenum Press, New York 1988

Authors and Affiliations

  • Robert S. Zucker
    • 1
  1. 1.Physiology-Anatomy DepartmentUniversity of CaliforniaBerkeleyUSA

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