Neurosecretion pp 181-189 | Cite as

Electrical Activity of Peptidergic Neurones and Its Relation to Hormone Release

  • D. A. Poulain
  • D. T. Theodosis


As all other neurones, the magnocellular neurones that secrete vasopressin and oxytocin generate action potentials and an obvious question is whether the electrical activity displayed by their cell bodies is necessary to bring about hormone release from their terminals. Another question quickly arises when one considers the temporal organization of these action potentials. As we will see, vasopressinergic and oxytocinergic neurones display several distinct patterns of electrical activity and one of the outcomes of recent research has been to show that such patterns of firing are particularly adapted to generate temporal patterns of hormone release necessary to meet the requirements of the target organ.


Firing Rate Hormone Release Interspike Interval Magnocellular Neurone Milk Ejection 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Plenum Press, New York 1988

Authors and Affiliations

  • D. A. Poulain
    • 1
  • D. T. Theodosis
    • 1
  1. 1.INSERM U.176Université of Bordeaux IIBordeaux CédexFrance

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