Effect of Exercise on Fuel Utilization and Insulin Requirements

  • Michael P. McLane
  • David L. Horwitz


The hormonal changes that occur during exercise are very important in control of fuel regulation. The observed changes in hormone concentrations, especially insulin, during exercise and the control of fuel regulation that is associated with these changes will be discussed in this chapter. A decrease in insulin concentration and an increase in glucagon concentration from concentrations during pre-exercise rest have been found in many studies.1–9 Other hormonal changes during exercise include elevations in growth hormone, cortisol, and catecholamines.5,6 More recent works have clarified the action of these regulatory hormones and have suggested that the decrease in insulin concentration 10–12 and the presence of glucagon 10,13,14 are essential for appropriate regulation of glucose production during exercise.


Glucose Utilization Glucose Production Glucagon Secretion Hepatic Glucose Production Insulin Requirement 
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Copyright information

© Plenum Publishing Corporation 1988

Authors and Affiliations

  • Michael P. McLane
    • 1
  • David L. Horwitz
    • 2
  1. 1.Department of Surgery and Department of PhysiologyLoyola University Medical CenterMaywoodUSA
  2. 2.Department of Medicine and Department of Nutrition and DieteticsUniversity of Illinois at ChicagoChicagoUSA

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