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Anabolic and Androgenic Steroids

  • Edward J. Keenan

Abstract

Androgens are steroid hormones that possess virilizing (androgenic) actions and, consequently, serve to stimulate differentiation and maintenance of the androgen-dependent tissues of the male reproductive system. These hormones also play an important role in facilitating protein synthesis (anabolic actions) in androgen-sensitive tissues such as skeletal muscle, the kidneys, and bone. The fact that testosterone and related hormones produce both androgenic and anabolic actions has been recognized since the 1930s. Not surprisingly, much effort has been devoted since then to the development of androgens that are devoid of virilizing actions. To a certain extent, this has been accomplished with the synthesis of 19-nortestosterone derivatives of the natural androgen, testosterone.

Keywords

Androgen Receptor Anabolic Steroid Male Reproductive System Anabolic Action Propionate Testosterone 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Suggested Readings

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Copyright information

© Plenum Publishing Corporation 1988

Authors and Affiliations

  • Edward J. Keenan
    • 1
  1. 1.Departments of Pharmacology, Surgery, and Medicine, School of MedicineThe Oregon Health Sciences UniversityPortlandUSA

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