An essential component of any chemical risk assessment is quantifying the nature and extent of exposure expressed in terms of concentration, dosage, or duration. In this chapter, we outline the structure of such exposure assessments using relatively simple partitioning models and provide an illustration of the underlying concepts. A full-scale exposure analysis may involve an extensive program of data collection, determination, and interpretation involving chemical analyses of various biotic and abiotic media, cal culation of the rates of emission into, and migration between, environmental media, and estimation of the toxic effects on organisms, populations, communities, and ecosystems. Examples are the series of reports published in the United States by the National Academy of Sciences/National Research Council and in Canada by the Environmental Secretariat of the National Research Council.
KeywordsPartition Coefficient Exposure Assessment Partitioning Model Chemical Partition Chemical Risk Assessment
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