Current Views of the Biology of Cancer

  • Ronald W. Hart
  • Angelo Turturro
Part of the Contemporary Issues in Risk Analysis book series (CIRA, volume 3)


In order to place the different methods used to estimate carcinogenic risk from chemical exposure into context, and to help decide on the best approach to improve this process, it is useful to discuss carcinogenesis with an emphasis on mechanism. Although the mecha nism of action of no carcinogen is completely characterized, the efforts over the last ten years have been very fruitful, and mechanistic explanations of a number of components in the grand design that is carcinogenesis have been described in detail.


Sister Chromatid Exchange Chemical Carcinogen Xeroderma Pigmentosum Flavin Adenine Dinucleotide Chemical Carcinogenesis 
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Copyright information

© Plenum Press, New York 1988

Authors and Affiliations

  • Ronald W. Hart
    • 1
  • Angelo Turturro
    • 1
  1. 1.National Center for Toxicological ResearchFood and Drug AdministrationJeffersonUSA

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