Biological Markers in Risk Assessment

  • Frederica P. Perera
Part of the Contemporary Issues in Risk Analysis book series (CIRA, volume 3)


Traditionally, the field of chemical carcinogenesis has relied upon estimates of adminis tered dose and/or human exposure in constructing dose-response curves and assessing cancer risk. Of far greater relevance to risk is the actual amount of carcinogen that has interracted with target cellular molecules such as DNA, RNA, or protein—the biologically effective dose of the carcinogenic substance.


Ethylene Oxide Biological Marker Sister Chromatid Exchange Protein Adduct Quantitative Risk Assessment 
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Copyright information

© Plenum Press, New York 1988

Authors and Affiliations

  • Frederica P. Perera
    • 1
  1. 1.Division of Environmental Science, School of Public HealthColumbia UniversityNew YorkUSA

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