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Biological Markers in Risk Assessment

  • Frederica P. Perera
Part of the Contemporary Issues in Risk Analysis book series (CIRA, volume 3)

Abstract

Traditionally, the field of chemical carcinogenesis has relied upon estimates of adminis tered dose and/or human exposure in constructing dose-response curves and assessing cancer risk. Of far greater relevance to risk is the actual amount of carcinogen that has interracted with target cellular molecules such as DNA, RNA, or protein—the biologically effective dose of the carcinogenic substance.

Keywords

Ethylene Oxide Biological Marker Sister Chromatid Exchange Protein Adduct Quantitative Risk Assessment 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1988

Authors and Affiliations

  • Frederica P. Perera
    • 1
  1. 1.Division of Environmental Science, School of Public HealthColumbia UniversityNew YorkUSA

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