Influence of Gas Physical Properties on Pulmonary Gas Exchange

  • Michael P. Hlastala
  • David D. Ralph
  • Albert L. Babb
Conference paper
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 227)


The gas exchange properties of the lung depend on the relative uniformity of the matching of ventilation and perfusion in the individual acinar units. The exchange of inert gases in a homogeneous acinar unit is dependent on the physical properties of those inert gases. This presentation deals with three aspects of the inert gas physical properties governing their exchange. The primary determinant of inert gas exchange is the solubility of the gas in blood. Second, gas exchange is weakly dependent on the molecular weight of the gas. Finally, the exchange of the very soluble inert gases depends on interaction of gas with the airways as air passes through the airways during inspiration and expiration.


Dead Space High Frequency Ventilation Breath Alcohol Concentration Bronchial Blood Flow Airway Temperature 
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Copyright information

© Plenum Press, New York 1988

Authors and Affiliations

  • Michael P. Hlastala
    • 1
  • David D. Ralph
    • 1
  • Albert L. Babb
    • 1
  1. 1.Departments of Chemical Engineering, Medicine Nuclear Engineering and Physiology and BiophysicsUniversity of WashingtonSeattleUSA

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