Structural vs Functional Limitations to Oxygen Transport: Is there a Difference?

  • James H. Jones
  • Richard H. Karas
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 227)

Abstract

The flow of O2 through the mammalian respiratory system has been described as occurring down a cascade of transport steps (Taylor and Weibel, 1981): pulmonary ventilation, pulmonary diffusion, circulatory convection, peripheral tissue diffusion, and reduction of the O2 by cytochrome oxidases on the inner cristae of mitochondria. When rates of O2 consumption (\(\rm\dot{v}\)O2) are at their maximum (\(\rm\dot{v}\)O2max), over 90% of the O2 flowing through the respiratory system is consumed by mitochondria in cardiac and skeletal muscle tissues (Mitchell and Blomqvist 1971).

Keywords

Convection Respiration Lism 

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Copyright information

© Plenum Press, New York 1988

Authors and Affiliations

  • James H. Jones
    • 1
  • Richard H. Karas
    • 2
  1. 1.Department of Physiological Sciences School of Veterinary MedicineUniversity of CaliforniaDavisUSA
  2. 2.Concord Field Station, Museum of Comparative ZoologyHarvard UniversityBedfordUSA

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