Mass Transfer of Liquids Across Biological Barriers
I believe that I was asked to address my colleagues in Cryobiology because of my interest in water and how it moves across biological barriers. Apparently freezing produces differential changes in the osmolarity of cell and medium and having water around which can crystallize is not a happy event. Therefore a major portion of this talk will be devoted to the transfer of water between compartments as a consequence of osmotic gradients.
KeywordsPermeability Coefficient Osmotic Gradient Permeable Solute Colloid Osmotic Pressure Osmotic Coefficient
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- 1.O. Kedem and A. Katchalsky, Thermodynamic analysis of the permeability of biological membranes to non-electrolytes. Biochim. et Biophys. Acta 27:229–246 (1958).Google Scholar
- 2.E. Ponder, “Hemolysis and Related Phenomena”, Grune & Stratton, Inc., New York, 83–101 (1948).Google Scholar
- 5.E. K. Hoffman, Role of separate K+ and Cl- channels and of Na+/Cl- cotransport in volume regulation in Ehrlich cells, Fed. Proc. 44:2513–2519 (1985).Google Scholar
- 6.F. W. Cope, Supramolecular biology: a solid state approach to ion and electron transport, Ann. N.Y. Acad. Sci. 204:416–433.Google Scholar
- 7.W. Drost-Hansen, in: “Chemistry of the Cell Interface”, Part B, edited by H.D. Brown, Academic Press, Inc., N.Y. (1971).Google Scholar
- 10.F. Franks and S. Mathias, “Biophysics of Water”, John Wiley & Sons, Ltd., New York, (1982).Google Scholar
- 19.P. Mazur, Kinetics of water loss from cells at sub-zero temperatures and the likelihood of intracellular freezing, J. Gen. Physiol. 47:405–419 (1931).Google Scholar
- 1.D.C. Chang, H.E. Rorschach, B.L. Nichols and C.F. Hazlewood, Implications of diffusion coefficient measurements for the structure of cellular water, Annals New York Acad. Sci 204:434 (1973).Google Scholar
- 4.L. Edelmann, Subcellular distribution of potassium in striated muscles, Scanning Electron Microscopy 11:875 (1984).Google Scholar