Biological Effects of Vitrification and Devitrification

  • Gregory M. Fahy
Part of the NATO ASI Series book series (NSSA, volume 147)


The physical nature of vitrification has been described in detail in previous chapters. Its relevance to cryobiology is attested to by the fact that papers describing its exploitation have been appearing with rapidly increasing frequency in recent years. This success is based to a large extent on a deeper and more complete understanding of non-equilibrium phase diagram behaviour and its biological implications, but many gaps in our basic understanding still need to be filled in. The purpose of this review is to document current knowledge concerning the biological acceptability of vitrification and the biological damage associated with devitrification and to relate existing knowledge to the problem of organ cryopreservation.


Mouse Embryo Vitrification Solution Early Blastocyst Kidney Slice Sperm Penetration 
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Copyright information

© Plenum Press, New York 1987

Authors and Affiliations

  • Gregory M. Fahy
    • 1
  1. 1.Jerome H. Holland Lab. for the Biomedical Sciences Transplantation LaboratoryAmerican Red CrossRockvilleUSA

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