Risk Assessment: Short-Term Exposure at Various Ages

  • David W. Gaylor
Part of the Basic Life Sciences book series (BLSC, volume 43)


Studies to estimate tumor incidence are frequently conducted in rodents exposed daily to a chemical for approximately two years. Dosing may be followed by a period of several weeks to allow tumors to develop before terminating the study. Exposure of humans to many carcinogens may occur for less than a lifetime; from occupations, changing lifestyles, or accidents. The question arises as to how to estimate the risk of tumors for short-term exposure at various ages from lifetime chronic bioassays.


Dose Rate Vinyl Chloride Longe Exposure Tumor Incidence Carcinogenic Process 


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Copyright information

© Plenum Press, New York 1988

Authors and Affiliations

  • David W. Gaylor
    • 1
  1. 1.National Center for Toxicological ResearchJeffersonUSA

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