Role of Lipid Peroxidation in Radiation Damage and Repair of Cell Membranes in the Thermophilic Bacterium Thermus Thermophilus
The thermophilic bacterium Thermus thermophilus HB-8, which does not contain unsaturated fatty acids, lost its ability to take up extracellular K+ in a temperature-dependent manner after its exposure to either UV radiation or cobalt-60 gamma rays. The dose response of HB-8 cells in terms of K+ permeability was not significantly different from that of an unsaturated fatty acid-requiring auxotroph of E. coli UFAts grown with linoleate. These results indicate that a radiation-induced change in K+ permeability of cell membranes is not attributable to lipid peroxidation.
KeywordsLipid Peroxidation Polyunsaturated Fatty Acid Unsaturated Fatty Acid Radiation Damage Membrane Damage
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