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Uremic Toxins pp 223-226 | Cite as

Identification of Two Uremic Toxins by Nuclear Magnetic Resonance and Mass Spectrometry

  • Jean-Pierre Monti
  • Philippe Gallice
  • Diane Braguer
  • Claude Durand
  • Antoine Murisasco
  • Aimé Crevat
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 223)

Abstract

A few uremic toxins (UT) previously called uremic middle molecules were isolated in pure form and identified In a previous study, by using a three step chromatographic separation we had isolated ten uremic toxins and had identified two of them The first is a double conjugate of glucuronidate-o-hydroxyhippuric acid identical to Fürst’s compound The second is a glucuronic acid conjugate of o-hydroxybenzoic acid. In the present paper, we report the identification by 1H nuclear magnetic resonance and mass spectrometry of two new uremic toxins represented by peaks 2-5-2 and 2-5-5.

Keywords

Nuclear Magnetic Resonance Uremic Toxin Coupling Feature Plasmatic Ultrafiltrate Positive Chemical Ionization 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1987

Authors and Affiliations

  • Jean-Pierre Monti
    • 1
  • Philippe Gallice
    • 1
  • Diane Braguer
    • 1
  • Claude Durand
    • 2
  • Antoine Murisasco
    • 2
  • Aimé Crevat
    • 1
  1. 1.Laboratoire de Biophysique, Faculté de PharmacieMarseille Cedex 5France
  2. 2.Service de NéphrologieHôpital de Sainte-MargueriteMarseilleFrance

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