A Purification Method by Uncoated Charcoal
The persistent state of sickness of patients in periodical dialysis, has been attributed, during the last years, to the retention of “uremic toxins” never identified with certainty. Parathyroid hormone, guanidinic compounds, aromatic substances, indacan, middle molecules, etc.have been proposed at various times the specific molecule responsible of the uremic state. Middle molecules which had in the past a very large following, have been recently defined elusive by many authors1-3.
KeywordsUremic Toxin Hepatic Coma Substitutive Treatment Persistent State Chromatographic Pattern
Unable to display preview. Download preview PDF.
- 4.B. H. Mamdani, M. Mashouf Shaykh,M. A. Evenson, G. Dunea. Chromato graphic studies of uremic plasma. Int.J.Art.Org. 2: 187 (1979)Google Scholar
- 5.T. M.S. Chang, C. Lister. Middle molecules in hepatic coma and uremia. Artif.Org. 4(suppl):169 (1980).Google Scholar
- 6.A. Saito, I. Kanazawa, T. G. Chung,K. Maeda. Analytic study for separation of middle molecules. Artif.Org. 4(suppl) 13: (1980).Google Scholar
- 7.T. M. S. Chang, P. Barre, S. Kuruvilla. Long-term reduced time hemo-perfusion-hemodialysis compared to standard dialysis:a preliminary crossover analysis. Trans.Amer.Soc.Art if.Intern.Organs 31: 572 (1985).Google Scholar
- 8.S. Shaldon, M. C. Beau, G. Claret, G. Deshodt, H. Miot, R. Oules, P. Raperez, C. Mion. Hemofiltration and sorbent regeneration of ultrafiltrate. EDTA XV: 20 (1978).Google Scholar
- 11.N. Cerulli, L. Politi, R. Scandurra. A chromatographic method to evaluate uremia and its substitutive treatments. Int.J.Artif.Org. 1986 (in press).Google Scholar