Syntheses and Structure-Activity Relationships of Thymopoietin
Two peptides, thymopoietins I and II, which are T-cell differentiating hormones of thymus were purified and characterized by Goldstein,1) using an in vitro neuromscular assay. Each peptide contains 49 amino acid residues and both peptides were shown to be related and to differ by only three amino acid residues.2)
KeywordsAmino Acid Residue Amino Acid Derivative Lower Potency Uremic Patient Uremic Toxin
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- The amino acid residues mentioned in this paper are L- configuration except for glycine. The abbreviations used to denote amino acid derivatives and peptides are those recommended by the IUPAC-IUB Joint Commission on Biochemical Nomenclature: European J. Biochem., 138: 9 (1984); Int. J. Peptide Protein Res., 24, No. 1 (1984).Google Scholar
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