Is Selenium Deficiency the Cause of Uraemic Cardiomyopathy?
We studied the relationship between serum selenium (Se) and left ventricular performance in 33 patients on maintenance haemodialysis. Low serum Se was frequent. However, there were no significant differences in echocardiographic indices of left ventricular function between patients with serum Se <0.9 umol/1 and those with serum Se >0.9 umol/1. We conclude that Se deficiency is not an important cause of cardiac failure in uraemia.
KeywordsSelenium Deficiency Serum Selenium Maintenance Haemodialysis Keshan Disease Home Parenteral Nutrition
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- 6.Leung A, Henderson I, Fell G, Hall D, Kennedy AC. Seleniumlenium deficiency in chronic uraemia and dialysis. Proc EDTA 1985;:1134–8Google Scholar
- 8.Van Fleet JF, Ferrans VJ, Ruth GR. Ultrastructural alterations in nutritional cardiomyopathy of selenium—vitamin E deficient swine. I Fiber lesions. Lab Invest 1977; 37 (2): 188–200Google Scholar