Advertisement

Retention Patterns

  • A. Schoots
  • R. Vanholder
  • S. Ringoir
  • C. Cramers
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 223)

Abstract

During the last century, there has been a continuous search for the toxins responsible for the uremic syndrome. Parallel to the development of analytical chemistry, many substances have been shown to accumulate in the body fluids of chronic uremic patients1.

Keywords

High Performance Liquid Chromatography High Performance Liquid Chromatography Hippuric Acid High Performance Liquid Chromatography Method Residual Renal Function 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    J. Bergstrom, P. Fürst, Uraemic toxins in: “Replacement of Renal Function by Dialysis”, W. Drukker, F.M. Parsons and J.F. Maher, eds., M. Nijhoff Publ.: 354 (1983).CrossRefGoogle Scholar
  2. 2.
    A.L. Babb, R.P. Popovich, T.G. Christopher and B.H. Scribner. The genesis of the square meter-hour hypothesis. Trans. Am. Soc. Artif. Int. Organs. Vol. XVII:81 (1971).Google Scholar
  3. 3.
    A. Schoots, F. Mikkers, C. Cramers, R. De Smet, and S. Ringoir. Uremic toxins and the elusive middle molecules. Nephron 38:1 (1984).PubMedCrossRefGoogle Scholar
  4. 4.
    P. Furst, J. Bergstrom, A. Gordon, E. Johnsson and L. Zimmerman. Separation of peptides of ‘middle’ molecular weight from biological fluids of patients with uremia. Kidney Int., 7:272 (1975).Google Scholar
  5. 5.
    J.L. Funck-Brentano, N.K. Man, A. Sausse, J. Zingraff, J. Boudet, A. Becker, G.F. Cueille. Characterization of a 1100–1300 MW uremic neurotoxin. Trans. Am. Soc. Artif. Int. Organs. 22:163 (1976).Google Scholar
  6. 6.
    A.C. Schoots, F.E.P. Mikkers, H.A. Claessens, R. De Smet, N. van Landschoot, and S.M.G. Ringoir. Characterization of uremic ‘middle molecular’ fractions by gas chromatography, mass spectrometry, isotachophoresis, and liquid chromatography. Clin. Chem., 28(1):45 (1982).PubMedGoogle Scholar
  7. 7.
    A.C. Schoots, H.R. Homan, M.M. Gladdines, C.A. Cramers, R. De Smet and S.M. Ringoir. Screening of UV-absorbing solutes in uremic serum by reversed HPLC. Change of blood levels in different therapies. Clin. Chimica Acta. 146:37 (1985).CrossRefGoogle Scholar
  8. 8.
    A. Schoots, R. Vanholder, P. Pieters, M. Piron, R. de Smet, C. Cramers and S. Ringoir. In vitro diffusive mass transfer of UV-absorbing and fluorescent uremic solutes on cuprophane membranes. Submitted for publication (1986).Google Scholar
  9. 9.
    P.C. Farrell, N.L. Gribb, D.L. Fry, R.P. Popovich, J.W. Broviac and A.L. Babb. A comparison of in vitro and in vivo solute-protein binding interactions in normal and uremic subjects. Trans. Am. Soc. Artif. Int. Organs. Vol. XVIII:268 (1972).CrossRefGoogle Scholar
  10. 10.
    P.C. Farrell, F.A. Gotch, J.H. Peters, B.J. Berridge and M. Lam. Binding of hippurate in normal plasma and in uremic plasma pre- and postdialysis. Nephron 20:40 (1978).PubMedCrossRefGoogle Scholar
  11. 11.
    W.J. Dorson, V.B. Pizziconi, C.N. Sizto, R.P. Radnoti, C.J. Zarembinski, and L.M. Aniuk. Solutizers as an adjunct to artificial organ treatment for bound chemicals. Trans. Am. Soc. Artif. Int. Organs. Vol. XXVI:116 (1980).Google Scholar
  12. 12.
    F.A. Gotch and J.A. Sargent. A mechanistic analysis of the National Cooperative Dialysis Study (NCDS). Kidney Int., 28:526 (1985).PubMedCrossRefGoogle Scholar
  13. 13.
    A.L. Babb, M.J. Strand, D.A. Uvelli, J. Milutinovic and B.H. Scribner. Quantitative description of dialysis treatment: A dialysis index. Kidney Int., 5:23 (1975).Google Scholar

Copyright information

© Plenum Press, New York 1987

Authors and Affiliations

  • A. Schoots
    • 1
  • R. Vanholder
    • 2
  • S. Ringoir
    • 2
  • C. Cramers
    • 1
  1. 1.Lab. of Instrumental AnalysisEindhoven University of TechnologyMB EindhovenThe Netherlands
  2. 2.Renal DivisionUniversity HospitalGhentBelgium

Personalised recommendations