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Uremic Toxins pp 125-129 | Cite as

Encephalopathic Toxicity: An Experimental Model of Uremia and Solute-Specific Dialysis

  • Paul E. Teschan
  • J. J. Lipman
  • P. Lawrence
  • D. BeBoer
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 223)

Abstract

The questions before us are: (1) How does renal failure make patients sick? and (2) How does dialysis make them better? Put another way: What is the connection, if any, between abnormal extracellular fluid (ECF) chemistry and patients’ symptomatic illness, since both are produced bys severe renal failure and both are improved by dialysis?

Keywords

Dialysis Session Uremic Toxin Severe Renal Failure Peritoneal Membrane Peritoneal Dialysis Catheter 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    G. E. Schreiner, Mental and personality changes in the uremic syndrome. Medical Annals of the District of Columbia, 28: 316–324 (1959).PubMedGoogle Scholar
  2. 2.
    P. E. Teschan, H. E. Ginn, J. R. Bourne, J. W. Ward, B. Hamel, J. C. Nunnally, M. Musso, and W. K. Vaughn, Quantitative indices of clinical uremia. Kidney International, 15: 676–697 (1979).PubMedCrossRefGoogle Scholar
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    P. E. Teschan, H. E. Ginn, J. R. Bourne, J. W. Ward, J. D. Schaffer, A prospective study of reduced dialysis, ASAIQ Journal, 6: 108–122 (1983).Google Scholar
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    D. DeBoer, J. J. Lipman, P. Lawrence, P. E. Teschan, Automated EEG monitoring system for quantification of uremic encephalopathy in a rodent model, Proceedings of the American Association of Medical Instrumentation, (1986).Google Scholar

Copyright information

© Plenum Press, New York 1987

Authors and Affiliations

  • Paul E. Teschan
    • 1
  • J. J. Lipman
    • 1
  • P. Lawrence
    • 1
  • D. BeBoer
    • 1
  1. 1.Division of NephrologyVanderbilt UniversityNashvilleUSA

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