A Peptide Binding Protein Which Plays a Role in Antigen Presentation
The helper T-cell recognition of globular protein antigens appears, in general, to require the intracellular processing of the antigen such that a peptide fragment containing the T-cell’s antigenic determinant is released, is transported to and held on the surface of an Ia expressing cell. However, the molecular details underlying these phenomena are largely unknown.
KeywordsPeptide Fragment Antigenic Peptide Antigenic Determinant Specific Peptide Binding Peptide Binding Protein
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- Lakey, E. K., Margoliash, E., and Pierce, S. K., 1986a, Identification of a peptide binding protein which plays a role in antigen presentation. Proc. Natl. Acad. Sci. USA, in press.Google Scholar