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The Protective Effects of BCG Vaccination against Tuberculosis

  • Donald W. Smith
  • Ernst H. Wiegeshaus
  • Mark L. Edwards
Part of the Infectious Agents and Pathogenesis book series (IAPA)

Abstract

An international conference, sponsored by the Fogarty International Center (FIC) of the National Institutes of Health in Washington, D.C., held in November 1987, entitled Research Toward the Global Control and Prevention of Tuberculosis, with an Emphasis on the Development of New Vaccines, would be expected to lead to an international research effort toward the eradication of tuberculosis. The research objectives of the FIC conference are similar to those of a conference organized in 1982 as the WHO Immunology of Tuberculosis program1 and therefore with the principal emphasis on the application of the technologies of genetic engineering and monoclonal antibody to the development of new antituberculosis vaccines. The objectives of these two research conferences suggest that tuberculosis control specialists are not satisfied with the protective effect of available BCG vaccines and the degree of their dissatisfaction is sufficiently great that scientists are being encouraged to develop new vaccines.

Keywords

Environmental Mycobacterium Respiratory Route Exogenous Reinfection Rational Animal Model Hematogenous Seeding 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1988

Authors and Affiliations

  • Donald W. Smith
    • 1
  • Ernst H. Wiegeshaus
    • 1
  • Mark L. Edwards
    • 1
  1. 1.Department of Medical MicrobiologyUniversity of Wisconsin-MadisonMadisonUSA

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