Mycobacterium-Induced Suppressor Cells and Their Clinical Importance

  • S. Orbach-Arbouys
Part of the Infectious Agents and Pathogenesis book series (IAPA)


The importance of suppressor cells in mycobacterium-bearing hosts arises from the fact that immunization against tuberculosis and leprosy using BCG vaccines protects in certain areas and fails to give protection in others.1,2 It has thus been suggested that the mycobacterium injection, rather than inducing a protective response, enhances the formation of suppressor cells3,4 which prevent the effector cells from either being formed or from expressing their activity.


Spleen Cell Suppressor Cell Mixed Lymphocyte Reaction Mycobacterium Bovis Leprosy Patient 
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Copyright information

© Plenum Press, New York 1988

Authors and Affiliations

  • S. Orbach-Arbouys
    • 1
  1. 1.Cancer and Immunogenetics InstitutePaul-Brousse HospitalVillejuifFrance

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