Ovarian and Decidual Relaxins in Human Pregnancy
The corpus luteum of pregnancy is one source of relaxin in the human (Weiss et al., 1976). Concentrations of relaxin-like immunoactivities in the systemic circulation have been measured by a porcine relaxin RIA (Quagliarello et al., 1979) and more recently by a RIA for synthetic human relaxin (Eddie et al., 1986). The levels of human relaxin in plasma are low in comparison to those in the sow. Peak values attained at between 12–20 weeks are approximately 1 ng/ml, declining thereafter and remaining at between 0.2–0.6 ng/ml for the rest of gestation.
KeywordsCorpus Luteum Fetal Membrane Cervical Dilatation Human Myometrium Human Relaxin
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