Abstract
Thecal cells are important intraovarian sources of androgens, providing substrate necessary for the synthesis of estradiol by granulosa cells (Armstrong and Dorrington, 1977), However, in addition to androgens, progesterone and estradiol are secreted by thecal cells of sows (Stoklosowa et al., 1982), cows (McNatty et al., 1984), monkeys (Vernon et al., 1983) and humans (McNatty et al., 1979). Although thecal steroidogenesis is regulated partly by circulating levels of luteinizing hormone (Baird and McNeilly, 1981; Merz et al., 1981; Carlson et al., 1984), the intrafollicular control of thecal steroidogenesis is unclear. As local steroidal and nonsteroidal factors can modify granulosa cell steroidogenesis in vitro (Hsueh et al., 1984; Tonetta and diZerega, 1986), the effects of physiological concentrations of steroids and gonadotropin on cultured porcine thecal cells were determined.
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© 1987 Plenum Press, New York
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Tonetta, S.A. (1987). Paracrine Control of 3β-Hydroxysteroid Dehydrogenase, 17,20-Lyase and Aromatase Enzyme Systems in Porcine Thecal Cells. In: Mahesh, V.B., Dhindsa, D.S., Anderson, E., Kalra, S.P. (eds) Regulation of Ovarian and Testicular Function. Advances in Experimental Medicine and Biology, vol 219. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5395-9_39
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DOI: https://doi.org/10.1007/978-1-4684-5395-9_39
Publisher Name: Springer, Boston, MA
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