Several GnRH Stimulation Frequencies Differentially Release FSH and LH from Isolated, Perfused Rat Anterior Pituitary Cells
Gonadotropin-releasing hormone (GnRH) releases both follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary, but not always at the same time. Both hormones surge on the day of proestrus in the rat, but only the FSH surge persists through estrous morning (Butcher et al., 1975; Smith et al., 1975). One way that a single releasing hormone could differentially affect two gonadotropins is by variation of the GnRH pulse pattern. Both frequency and amplitude have been altered to release more FSH than LH (Wildt et al., 1981; Wise et al., 1978).
KeywordsLuteinizing Hormone Estrous Cycle Releasable Luteinizing Hormone Anterior Pituitary Cell Luteinizing Hormone Release
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- Morrison DF, 1967. Multivariate Statistical Methods. New York:McGraw-Hill, pp. 141–148Google Scholar
- Savoy-Moore RT, Swartz KH, 1986. Isolated, perfused rat anterior pituitary cells can differentially release FSH following GnRH stimulation. Abstract 128, Society for the Study of Reproduction 19th Annual MeetingGoogle Scholar