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Several GnRH Stimulation Frequencies Differentially Release FSH and LH from Isolated, Perfused Rat Anterior Pituitary Cells

  • R. T. Savoy-Moore
  • K. H. Swartz
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 219)

Abstract

Gonadotropin-releasing hormone (GnRH) releases both follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary, but not always at the same time. Both hormones surge on the day of proestrus in the rat, but only the FSH surge persists through estrous morning (Butcher et al., 1975; Smith et al., 1975). One way that a single releasing hormone could differentially affect two gonadotropins is by variation of the GnRH pulse pattern. Both frequency and amplitude have been altered to release more FSH than LH (Wildt et al., 1981; Wise et al., 1978).

Keywords

Luteinizing Hormone Estrous Cycle Releasable Luteinizing Hormone Anterior Pituitary Cell Luteinizing Hormone Release 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Plenum Press, New York 1987

Authors and Affiliations

  • R. T. Savoy-Moore
    • 1
  • K. H. Swartz
    • 1
  1. 1.Departments of OB/GYN and PhysiologyWayne State UniversityDetroitUSA

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