Comparative Aspects of the Regulation of Corpus Luteum Function in Various Species

  • Fredrick Stormshak
  • Mary B. Zelinski-Wooten
  • Salah E. Abdelgadir
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 219)


Central to understanding the pivotal role of the corpus luteum in governing reproductive cycles of mammals has been the study of those factors that control the function of this gland. Research on control of luteal function has encompassed a broad spectrum of mammalian taxa and has evolved from early studies to identify the source and nature of controlling factors to present day attempts to resolve their action at the level of the luteal cell. From this research data have emerged leading to the realization that among mammals a diversity of factors regulate the function of the corpus luteum. The fact that function of the corpus luteum, in most mammals, is influenced by hormones from several sources, namely the pituitary gland, uterus and placenta, makes this organ truly unique among endocrine glands. As the student of the corpus luteum is well aware, some of these hormones are involved in promoting steroidogenesis and(or) prolonging the life span of the corpus luteum while others serve to provoke its demise. In recent years several excellent reviews have appeared that discuss differences among mammals in regard to the hormonal regulation of luteal function (Rothchild, 1981; Keyes et al., 1983; Niswender et al., 1985; Khan-Dawood and Dawood, 1986). Consequently, certain portions of the present treatise on luteal function may appear to be redundant. Although old ground may be trod upon once again, an effort will be made to present new information.


Luteinizing Hormone Corpus Luteum Estrous Cycle Luteal Cell Luteinizing Hormone Receptor 
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Copyright information

© Plenum Press, New York 1987

Authors and Affiliations

  • Fredrick Stormshak
    • 1
  • Mary B. Zelinski-Wooten
    • 1
  • Salah E. Abdelgadir
    • 1
  1. 1.Departments of Animal Science and Biochemistry and BiophysicsOregon State UniversityCorvallisUSA

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