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Storage and Translation of Ferritin Messenger RNA

  • Chapter
Translational Regulation of Gene Expression

Abstract

Early in evolution, most life forms became dependent on iron proteins for such reactions as electron transfer, nitrogen reduction, and DNA synthesis (ribonucleotide reductase) because of the abundance and the redox properties of iron. When the use of H2O as a source of hydrogen for photosynthesis began 2.5 billion years ago, a profound change in the environment was wrought: dioxygen was released as a by-product. For the first approximately 200–300 million years thereafter, the oxygen content of the atmosphere changed little because oxygen was consumed in the conversion of ferrous to ferric.1 However, cellular metabolism changed dramatically. Iron was still abundant, but instead of the soluble ferrous iron, the cells had to accommodate to insoluble ferric with a solubility of 10−18 M.2 Ferritin maintains a soluble reservoir of ferric iron that in cells specialized for iron storage, can be equivalent to 10−5 M.3 While it is not known whether ferritin existed before oxygen-evolving photosynthesis, the need for ferritin increased dramatically at that time.

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References

  1. Walker, J. C. G., The Evolution of the Atmosphere, p. 262, Macmillan, New York.

    Google Scholar 

  2. Biederman, G., Schindler, P., 1957, Acta Chem. Scand. 11: 731.

    Google Scholar 

  3. Theil, E. C., Brown, J. E., 1977, in: Proteins of Iron Metabolism (E. B. Brown, ed.), p. 99, Grune and Stratton, New York.

    Google Scholar 

  4. Theil, E. C., 1987, Ann. Rev. Biochem. 56: 289–315.

    PubMed  CAS  Google Scholar 

  5. Munro, H. N., Binder, M. C., 1978, Physiol. Rev. 58: 317.

    PubMed  CAS  Google Scholar 

  6. Clegg, G. A., Fitton, J. E., Harrison, P. M., Treffry, A., 1980, Prog. Biophys. Mol. Biol. 36: 53.

    CAS  Google Scholar 

  7. Aisen, P., Listowsky, I., 1980, Annu. Rev. Biochem. 49: 357.

    PubMed  CAS  Google Scholar 

  8. Theil, E. C., 1973, Dev. Biol. 34: 282.

    PubMed  CAS  Google Scholar 

  9. Theil, E. C., 1976, Br. J. Haematol. 33: 437.

    PubMed  CAS  Google Scholar 

  10. Theil, E. C., Tosky, G. M., 1979, Dev. Biol. 69: 666.

    PubMed  CAS  Google Scholar 

  11. Theil, E. C., Brenner, W. E., 1981, Dev. Biol. 84: 481.

    PubMed  CAS  Google Scholar 

  12. Under, M. C., Moor, J. R., Soctt, L. E., Munro, H. N., 1972, Biochem. J. 129:455.

    Google Scholar 

  13. Vulimiri, L., binder, M. C., Munro, H. N., 1977, Biochim. Biophys. Acta 497: 280.

    PubMed  CAS  Google Scholar 

  14. Granick, S., 1946, J. Biol. Chem. 164: 737.

    PubMed  CAS  Google Scholar 

  15. Drysdale, J. W., Munro, H. N., 1966, J. Biol. Chem. 241: 3630.

    PubMed  CAS  Google Scholar 

  16. Theil, E. C., 1978, J. Biol. Chem. 253: 2902.

    PubMed  CAS  Google Scholar 

  17. Schaefer, F. V., Theil, E. C., 1981, J. Biol. Chem. 256: 1711.

    PubMed  CAS  Google Scholar 

  18. Valaitis, A. P., Theil, E. C., 1984, J. Biol. Chem. 259: 779.

    PubMed  CAS  Google Scholar 

  19. Ihara, K., Maeguchi, K., Young, C. T., Theil, E. C., 1984. J. Biol. Chem. 259: 278.

    PubMed  CAS  Google Scholar 

  20. Brown, J. E., Theil, E. C., 1978, J. Biol. Chem. 253: 2673.

    PubMed  CAS  Google Scholar 

  21. Yamada, H., Gabuzda, T. G., 1974, J. Lab. Clin. Med. 83: 478.

    PubMed  CAS  Google Scholar 

  22. Neckars, L. M., and Cossman, J., 1983 Proc. Natl. Acad. Sci. USA 80:3494.

    Google Scholar 

  23. Dorner, M. H., Silverstone, A., Nishiya, K., de Sostoa, A., Munn, G., de Sousa, M., 1980, Science 209: 1019.

    PubMed  CAS  Google Scholar 

  24. Theil, E. C., 1981, in: Hemoglobins in Development and Differentiation (G. Stamatoyannopoulos A. Nienhuis, eds.), p. 423, Alan R. Liss, New York.

    Google Scholar 

  25. Macey, D. J., Smalley, S. R., Potter, I. C., Cake, M. H., 1987, J. Сотр. Physiol. Ser. В (in press).

    Google Scholar 

  26. Sayers, D. E., Theil, E. C., Rennick, F. J., 1983, J. Biol. Chem. 258: 14, 076.

    Google Scholar 

  27. Treffry, A., Sowerby, J., Harrison, P. M., 1979, FEBS Lett. 100: 33.

    PubMed  CAS  Google Scholar 

  28. Jones, T., Spencer, R., Walsh, C., 1978, Biochemistry 17: 4011.

    PubMed  CAS  Google Scholar 

  29. Mertz, J. R., Theil, E. C., 1983, J. Biol. Chem. 258: 11, 719.

    Google Scholar 

  30. Banyard, S. H., Stammers, D. K., Harrison, P. M., 1978, Nature (London) 271: 282.

    CAS  Google Scholar 

  31. Rice, D. W., Ford, G. C., White, J. L., Smith, J. M. A., Harrison, P. M., 1983, in: Advances in Inorganic Biochemistry, Vol. 5 (E. C. Theil, G. L. Eichhorn, L. G. Marzilli, eds.), p. 39, Elsevier/North-Holland, New York.

    Google Scholar 

  32. Didsbury, J. R., Theil, E. C., Kaufman, R. E., Dickey, L. F., 1986, J. Biol. Chem. 261: 949.

    PubMed  CAS  Google Scholar 

  33. Brown, A. J. P., Leibold, E. A., Munro, H. N., 1983, Proc. Natl. Acad. Sci. U.S.A. 80: 1265.

    PubMed  CAS  Google Scholar 

  34. Costanzo, F., Santoro, C., Colantuoni, V., Bensi, G., Raugei, G., Romano, V., Cortese, R., 1984, Eur. Mol. Biol. Org. J. 3: 23.

    CAS  Google Scholar 

  35. Dorner, M. H., Salfeld, J., Will, H., Leibold, E. A., Vass, J. K., Munro, H. N., 1985, Proc. Natl. Acad. Sci. U.S.A. 82: 3139.

    PubMed  CAS  Google Scholar 

  36. Boyd, D., Vecoli, C., Belcher, D. M., Jain, S., Drysdale, J. W., 1985, J. Biol. Chem. 260: 11, 755.

    Google Scholar 

  37. Jain, S. K., Barrett, K. J., Boyd, D., Favreau, M. F., Crampton, J., Drysdale, J. W., 1985, J. Biol. Chem. 260: 11, 762.

    Google Scholar 

  38. Chou, C.-C., Gatti, R. A., Fuller, M. L., Concannon, P., Wong, A., Chado, S., Davis, R. C., Salser, W. A., 1986, Mol. Cell. Biol. 56: 566–573.

    Google Scholar 

  39. Cragg, S. J., Wagstaff, M., Worwood, M., 1980, Clin. Sci. 58: 259.

    PubMed  CAS  Google Scholar 

  40. Cragg, S. J., Wagstaff, M., Worwood, M., 1985, Biochem. J. 199: 565.

    Google Scholar 

  41. Bottomly, S., Personal communication.

    Google Scholar 

  42. Drysdale, J. W., 1977, in: Iron Metabolism, p. 41, Ciba Foundation Symposium, Elsevier/North-Holland, Amsterdam.

    Google Scholar 

  43. Lavoie, D. J., Ishikawa, K., Listowsky, I., 1978, Biochemistry 17: 5448.

    PubMed  CAS  Google Scholar 

  44. Gowan, L. K., Collawn, J. F., Fenderson, M. B., Fish, W. W., 1983, Fed. Proc. Fed. Am. Soc. Exp. Biol. 42 (8): 2986 (abstract).

    Google Scholar 

  45. Watanabe, N., Drysdale, J., 1983, Biochim. Biophys. Acta 743: 98.

    PubMed  CAS  Google Scholar 

  46. Binder, M. C., Nagel, G. M., Roboz, M., Hungerford, D. M., Jr., 1981, J. Biol. Chem. 256: 9104.

    Google Scholar 

  47. Munro, H. N., Leibold, E. A., Vass, J. K., Aziz, N., Rogers, J., Murray, M., White, K., 1985, in: Proteins of Iron Storage and Transport (G. Spik, J. Montreuil, R. R. Crichton, J. Mazurier, ed.), p. 331, Elsevier, Amsterdam.

    Google Scholar 

  48. Sreedharan, S., Didsbury, J. R., Theil, E. C., Kaufmann, R. L., 1986, Fed. Proc. Fed. Am. Soc. Exp. Biol, (abstract) 45 (6): 1699.

    Google Scholar 

  49. Harrison, P. M., Fischbach, F. A., Hoy, T. G., Haggis, G. A., 1967, Nature (London) 216: 1188.

    CAS  Google Scholar 

  50. Towe, K. M., Bradley, W. W., 1967, J. Colloid. Interface Sci. 24: 384.

    CAS  Google Scholar 

  51. Theil, E. C., Sayers, D. E., Brown, M. A., 1979, J. Biol. Chem. 254: 8132.

    PubMed  CAS  Google Scholar 

  52. Crichton, R. R., Roman, F., Roland, F., 1980, FEBS Lett. 110: 271.

    PubMed  CAS  Google Scholar 

  53. Crichton, R. R., Roman, F., Roland, F., 1980, J. Inorg. Biochem. 13: 305.

    PubMed  CAS  Google Scholar 

  54. Hoy, T. G., Harrison, P. M., Shabbir, M., Macara, I. G., 1974, Biochemistry 137: 67.

    CAS  Google Scholar 

  55. Chasteen, N. D., Theil, E. C., 1982, J. Biol. Chem. 257: 7672.

    PubMed  CAS  Google Scholar 

  56. Wauters, M., Michelson, A. M., Crichton, R. R., 1978, FEBS Lett. 91: 276.

    PubMed  CAS  Google Scholar 

  57. Macara, I. G., Hoy, T. G., Harrison, P. M., 1973, Biochem. J. 135: 785.

    Google Scholar 

  58. Theil, E. C., Sayers, D. E., Yang, C. Y., 1985, in: Proteins of Iron Storage and Transport (G. Spik, J. Montreuil, R. R. Crichton, J. Mazurier, eds.), p. 81, Elsevier, Amsterdam.

    Google Scholar 

  59. Harrison, P. M., White, J. L., Smith, J. M. A., Farrants, G. W., Ford, G. C., Rice, D. W., Addison, J. M., Treffry, A., 1985, in: Proteins of Iron Storage and Transport (G. Spik, J. Montreuil, R. R. Crichton, J. Mazurier, eds.), p. 331, Elsevier, Amsterdam.

    Google Scholar 

  60. Theil, E. C., 1976, Br. J. Haematol. 33: 437.

    PubMed  CAS  Google Scholar 

  61. Yoshino, Y., Manis, J., Schachter, D., 1968, J. Biol. Chem. 243: 2911.

    PubMed  CAS  Google Scholar 

  62. Yu, F.-L., Fineberg, R. A., 1965, J. Biol. Chem. 240: 2083.

    PubMed  CAS  Google Scholar 

  63. Bothwell, T. H., Charlton, R. W., Cook, J. D., Finch, C. A., 1979, Iron Metabolism in Man p. 327, Blackwell, Oxford.

    Google Scholar 

  64. Bothwell, T. H., Charlton, R. W., Cook, J. D., Finch, C. A., 1979, Iron Metabolism in Man, p. 303, Blackwell, Oxford.

    Google Scholar 

  65. Bothwell, T. H., Charlton, R. W., Cook, J. D., Finch, C. A., 1979, Iron Metabolism in Man, p. 121, Blackwell, Oxford.

    Google Scholar 

  66. Goya, N., Miyazaki, S., Kodate, S., Ushino, B., Blood 40: 239.

    Google Scholar 

  67. McKnight, G. S., Lee, D. C., Palmiter, R. C., 1980, J. Biol. Chem. 256: 148.

    Google Scholar 

  68. Lum, J. B., Yang, F., Bowman, B., 1985, in: Proteins of Iron Storage and Transport (G. Spik, J. Montreuil, R. R. Crichton, J. Mazurier, eds.), p. 357, Elsevier, Amsterdam.

    Google Scholar 

  69. Bomford, A., Conlon-Hollingshead, C., Munro, H. N., 1981, J. Biol. Chem. 256: 948.

    PubMed  CAS  Google Scholar 

  70. Watanabe, N., Drysdale, J., 1981, Biochem. Biophys. Res. Commun. 103: 207.

    PubMed  CAS  Google Scholar 

  71. Van Wyck, C. P., Linder-Horowitz, M., Munro, H. N.. 1971, J. Biol. Chem. 246: 1025.

    Google Scholar 

  72. Zahringer, R. J., Baliga, B. S., Munro, H. N., 1976, Proc. Natl. Acad. Sci. U.S.A. 73: 857.

    PubMed  CAS  Google Scholar 

  73. Shull, G. E., Theil, E. C., 1983, J. Biol. Chem. 258: 7921.

    PubMed  CAS  Google Scholar 

  74. Shull, G. E., Theil, E. C., 1982, J. Biol. Chem. 257: 14, 187.

    Google Scholar 

  75. Showman, R. M., Wells, D. E., Anstrom, J., Hursh, D., Raff, R. A., 1982, Proc. Natl. Acad. Sci. U.S.A. 79: 5944.

    PubMed  CAS  Google Scholar 

  76. Dickey, L. F., Wang, Y.-H., Wortman, I., Shull, G. E., 1987, Fed. Proc. 46: 1797 (abstract).

    Google Scholar 

  77. Seckbach, J., 1968, J. Ultrastruct. Res. 22: 413.

    PubMed  CAS  Google Scholar 

  78. Whatley, J. M., 1977, New Phytol. 78: 407.

    Google Scholar 

  79. Hyde, B. B., Hodge, A. J., Kahn, A., Birnstill, M. L., 1963, J. Ultrastruct. Res. 9: 248.

    CAS  Google Scholar 

  80. Ko, M. P., Huang, P.-Y., Huang, K. S., Barker, K. P., 1985, Phytopathology 75: 159.

    CAS  Google Scholar 

  81. van der Mark, F., Bienfait, F., van den Ende, H., 1983, Biochem. Biophys. Res. Commun. 115: 463.

    PubMed  Google Scholar 

  82. van der Mark, F., van den Briel, J. W., van Oers, A. M., Bienfait, H. F., 1982, Planta 156: 341.

    Google Scholar 

  83. van der Mark, F., van den Briel, W., Huisman, H. G., 1983, Biochem. J. 214: 943.

    PubMed  Google Scholar 

  84. Drysdale, J., Jain, S. K., Boyd, D., Barrett, K. J., Vecoli, C., Belcher, D. M., Beaumont, C., Worwood, M., Lebo, R., McGill, J., Crampton, J., 1985, in: Proteins of Iron Storage and Transport (G. Spik, J. Montreuil, R. R. Crichton, J. Mazurier, eds.), p. 343, Elsevier, Amsterdam.

    Google Scholar 

  85. Dickey, L. F., Sreedharan, S., Theil, E. C., Didsbury, J. R., Wang, Y.-W., Kaufman, R. E., 1987, J. Biol. Chem. (in press).

    Google Scholar 

  86. Walden, W. E., Thach, R. E., 1986, Biochemistry 25: 2033–2041.

    PubMed  CAS  Google Scholar 

  87. Durnam, D. M., Palmiter, R. D., 1981, J. Biol. Chem. 256: 5712.

    PubMed  CAS  Google Scholar 

  88. Bryan, S. E., 1981, in: Advances in Inorganic Biochemistry, Vol. 2 (G. L. Eichhorn,L. G. Marzilli, eds.), p. 87, Elsevier, New York.

    Google Scholar 

  89. Zamenhof, S., Griboff, G., Marullo, N., 1954, Biochem. Biophys. Acta. 13: 459.

    PubMed  CAS  Google Scholar 

  90. D’Andréa, A. D., Haseltine, W. A., 1978, Proc. Natl. Acad. Sci. U.S.A. 75: 3608.

    PubMed  Google Scholar 

  91. Walling, C., 1975, Acct. Chem. Res. 8: 125.

    CAS  Google Scholar 

  92. Dabrowiak, J. C., 1982, in: Advances in Inorganic Biochemistry, Vol. 4 (G. L. Eichhorn, L. G. Marzilli, eds.), p. 69, Elsevier, New York.

    Google Scholar 

  93. Burger, R. M., Peisach, J., Blumberg, W. E., Horwitz, S. B., 1979, J. Biol. Chem. 254: 10, 906.

    Google Scholar 

  94. Sauville, E. A., Peisach, J., Horwitz, S. B., 1978, Biochemistry 17: 2740.

    Google Scholar 

  95. Murray, V., Martin, R. F., 1985, J. Biol. Chem. 260: 10, 389.

    Google Scholar 

  96. Neilands, J., 1982, Annu. Rev. Microbiol. 36: 285.

    PubMed  CAS  Google Scholar 

  97. Schneider, R. J., Weinberger, C., Shenk, T., 1984, Cell 37: 291.

    PubMed  CAS  Google Scholar 

  98. Medford, R. M., Nguyen, H. T., Nadal-Ginard, B., 1983, J. Biol. Chem. 258: 11, 063

    Google Scholar 

  99. Nguyen, H. T., Medford, R. M., Nadal-Ginard, B., 1983, Cell 34: 281.

    PubMed  CAS  Google Scholar 

  100. McGarry, T. J., Lindquist, S., 1985, Cell 42: 903.

    PubMed  CAS  Google Scholar 

  101. McGuire, D., Olson, C. D., Towle, H. C., Dempsey, M. E., 1984, J. Biol. Chem. 259: 5368.

    PubMed  CAS  Google Scholar 

  102. Mueckler, M., Merrill, M., Pitot, H. C., 1984, J. Biol. Chem. 258: 6109.

    Google Scholar 

  103. Theil, E. C., 1975, Dev. Biol. 46: 343.

    PubMed  CAS  Google Scholar 

  104. Drysdale, J. W., Olafsdottier, E., Munro, H. N., 1968, J. Biol. Chem. 243: 552.

    PubMed  CAS  Google Scholar 

  105. Lingrel, J. B., Lowenhaupt, K., Haynes, J. R., Rosteck, P., Kalb, V. F., Smith, K., 1979, in: Cellular and Molecular Regulation of Hemoglobin Switching (G. Stamatoyannopoulos, A. Nienhuis, eds.), p. 675, Grune and Stratton, New York.

    Google Scholar 

  106. Lodish, H. F., Desalu, O., 1973, J. Biol. Chem. 258: 3520.

    Google Scholar 

  107. Theil, E. C., Shull, M. M., Shull, G. E., 1984, Fed. Proc. Fed. Am. Soc. Exp. Biol. 43 (7): 1976 (abstract).

    Google Scholar 

  108. Yamada, Y., Mudryj, M., de Crombrugghe, B., 1983, J. Biol. Chem. 258: 14, 914.

    Google Scholar 

  109. Pabo, C. O., Sauer, R. T., 1984, Archives Biochem. Biophys. 53: 293.

    CAS  Google Scholar 

  110. Allan, M., Grindlay, G. J., Stefani, L., Paul, J., 1982, Nucleic Acids Res. 10: 5133.

    Google Scholar 

  111. Malek, L. T., Eschenfeldt, W. H., Munns, T. W., Rhoads, R. E., 1981, Nucleic Acids Res. 9: 1657.

    PubMed  CAS  Google Scholar 

  112. Benyajati, C., Spoerel, N., Haymerle, H., Ashburner, M., 1983, Cell 33: 125.

    PubMed  CAS  Google Scholar 

  113. Reynolds, G. A., Goldstein, J. L., Brown, M. S., 1985, J. Biol. Chem. 260: 10, 369.

    Google Scholar 

  114. Colombo, M., Constanzo, F., Santoro, C., Marone, M., Staempfli, S., Cortese, R., 1985, Quad. Ligand Q. 4 (Suppl. 2): 57.

    Google Scholar 

  115. Fowler, V. M., Davis, J. Q., Bennett, V., 1985, J. Cell Biol. 100: 47.

    PubMed  CAS  Google Scholar 

  116. Worwood, M., Brook, J. D., Cragg, S. J., Hellkuhl, B., Jones, B. M., Perera, P., Roberts, S. H., Shaw, D. J., 1985, Hum. Genet. 69: 371.

    PubMed  CAS  Google Scholar 

  117. Caskey, J., Jones, C., Miller, Y. E., Seligman, P. A., 1983, Proc. Natl. Acad. Sci. U.S.A. 80: 482.

    PubMed  CAS  Google Scholar 

  118. Teraoka, S., Concannon, P., Chou, C.-C., Fuller, M., Chada, S., Wong, A., Wright, J., Kania, S., Snyder, C., Hwa, J., Davis, R., Nelson, R., Thomason, A., Salser, W., 1985, in: Proteins of Iron Storage and Transport (G. Spik, J. Montreuil, R. R. Crichton, J. Mazurier, eds.), p. 349, Elsevier, Amsterdam.

    Google Scholar 

  119. Santoro, C., Marone, M., Ferrone, M., Constanso, F., Colombo, M., Mingaui, C., Cortese, R., Silengo, L., 1986, Nucleic Acids Res. 19: 2863.

    Google Scholar 

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  1. Department of Biochemistry, North Carolina State University, Raleigh, North Carolina, 27695, USA

    Elizabeth C. Theil

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  1. Department of Developmental Genetics and Anatomy, School of Medicine, Case Western Reserve University, Cleveland, Ohio, 44106, USA

    Joseph Ilan

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Theil, E.C. (1987). Storage and Translation of Ferritin Messenger RNA. In: Ilan, J. (eds) Translational Regulation of Gene Expression. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5365-2_7

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