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Gene Expression in Muscle

The Role of Small RNAs in the Expression of Muscle-Specific Proteins
  • Diane J. Zezza
  • Barbara Mroczkowski
  • Stuart M. Heywood

Abstract

It has been proposed1 and a great deal of evidence has accumulated that gene expression in eukaryotes may result from the use of a variety of regulatory mechanisms ranging from the recognition of specific DNA sequences to differential turnover rates of proteins. Such a cascade of controls ultimately defines the phenotype of any given cell type. Likewise, muscle cells will utilize a particular set of regulatory mechanisms to synthesize, assemble, and maintain the proteins that constitute the contractile apparatus. This, of course, must involve a sequential and tissue-specific expression of the various isoforms of these muscle-specific proteins during development.

Keywords

Small RNAs Myosin Heavy Chain Sucrose Density Gradient Nontranslated Region Myosin Heavy Chain Gene Expression 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1987

Authors and Affiliations

  • Diane J. Zezza
    • 1
  • Barbara Mroczkowski
    • 1
  • Stuart M. Heywood
    • 1
  1. 1.Department of Molecular and Cell BiologyUniversity of ConnecticutStorrsUSA

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