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The Molecular Biology of Adenoviruses

  • Arnold J. Levine
Part of the NATO ASI Series book series (NSSA, volume 136)

Abstract

The adenoviruses were discovered in 1953–54 by two independent groups studying respiratory diseases (1, 2). W. Rowe and his collegues at the National Institute of Health in Bethesda, MD, USA, developed an experimental method for culturing adenoids that were removed from children. Cells derived from such cultured tissues subsequently liberated a viral agent which then destroyed these cells. The agent was called “the adenoid degenerating agent” or AD agent (1). At about the same time M. Hilleman and his research group at Merck Sharp and Dohme isolated a virus from the throat washings of military recruits (2). This virus replicated in and killed human HeLa cells in culture and was called “the respiratory illness agent” or RI agent (2). The RI agent and the AD agent were rapidly shown to be related to each other and the name adenoviruses was adopted to describe this group of viruses. Employing immunological reagents to classify viral antigens a large number of related adenoviruses, with a common group specific antigen, were detected in humans (3), monkies (4), dogs (5), mice (6), cattle (7), and birds (8). The adenovirus group now has over 90 members (9) with more than 40 distinct isolates of human origin (3). These viruses all share a common group specific antigen which is the exon virion subunit or virion surface capsid. Individual viruses are identified by a type specific antigen on the virion fiber protein which is responsible for absorption of viruses to cells.

Keywords

Cold Spring Harbor Adenovirus Type Terminal Protein Late mRNAs Major Histocompatibility Antigen 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1).
    Rowe, W.P., R.J. Huebner, K.K. Gillmore, R.H. Parrott, and T.G. Ward, (1953). Proc. Soc. Exp. Biol. Med. 84: 570.PubMedGoogle Scholar
  2. 2).
    Hillman, M.R. and J.H. Werner, (1954), Proc. Soc. Exp. Biol. Med. 85. 183.Google Scholar
  3. 3).
    Wadell, G., (1984) in Curr. Top. Micro. Imm. 110, Ed., W. Doerfler, The Mol. Biol. Adenoviruses 2, Springer-Verlag, New York, 191–220.Google Scholar
  4. 4).
    Hull, R.N., J.R. Minner and C.C. Mascoli, (1958), Am J. Hyg. 68. 31.PubMedGoogle Scholar
  5. 5).
    Kapsenberg, J.G. (1959). Proc. Soc. Exp. Biol. Med. 101: 611.PubMedGoogle Scholar
  6. 6).
    Hartley, J.W. and W.P. Rowe. (1960). Virol. 11: 645.CrossRefGoogle Scholar
  7. 7).
    Klein, M., E. Ealey and J. Zellat (1959). Proc. Soc. Exp. Biol. Med. 102: 1.PubMedGoogle Scholar
  8. 8).
    Robinson, A.J., H.B. Younghusband and A.J.D. Bellett, (1973). Virol. 56: 54.CrossRefGoogle Scholar
  9. 9).
    Doerfler, W. (Ed.), Curr. Top. Micro. Imm., Vols: 109, 110 and 111, The Mol. Biol. Adenoviruses 1, 2, 3, Springer Verlag, New York.Google Scholar
  10. 10).
    Horne, R.W., S. Bonner, A.P. Waterson and P. Wildy, (1959). J. Mol. Biol., 1:84.CrossRefGoogle Scholar
  11. 11).
    Tooze, J. (Ed.). Mol. Biol. Tumor Viruses, 2nd ed., revised. The DNA Tumor Viruses, Cold Spring Harbor Press, New York, Chapters 8, 9, 10, 11.Google Scholar
  12. 12).
    Brown, D.T., M. Westphal, B.T. Burlingham, U. Winterhoff and W. Doerfler, (1975). J. Virol. 16: 366.PubMedGoogle Scholar
  13. 13).
    Philipson, L., (1983), Curr. Top. Micro. Imm. 109: Ed., W. Doerfler, Springer-Verlag, New York., pp. 1.Google Scholar
  14. 14).
    Green, M., M. Pina, R. Kimes, P.C. Wensink, L.A. Machattie and C.A. Thomas, (1967). Proc. Natl. Acad. Sci. USA 5b7: 1322.Google Scholar
  15. 15).
    Green, M. (1970). Ann. Rev. Biochem. 39: 701.PubMedCrossRefGoogle Scholar
  16. 16).
    Wolfson, J. and Dressier, D. (1972). Proc. Natl. Acad. Sci. 69: 3054.PubMedCrossRefGoogle Scholar
  17. 17).
    Van Ormondt, H. and F. Galibert, (1984). Curr. Top. Microbiol. Imm., Ed. W. Doerfler, Vol. 110, Springer-Verlag, New York, 73–141.Google Scholar
  18. 18).
    Sussenbach, J.S. and P.C. vander Vleet, (1983), Curr. Top. Microbiol. Imm., 109, Ed. W. Doerfler, Springer-Verlag, New York, 36.Google Scholar
  19. 19).
    Futterer J. and Winnocker, E.L. (1984). Curr. Top. Microbiol. Imm. III, Ed. W. Doerfler, Springer-Verlag, New York, 41–58.Google Scholar
  20. 20).
    Rosen, L. (1960). Am. J. Hyg. 71: 120–128.PubMedGoogle Scholar
  21. 21).
    Huebner, R.J. (1967). M. Pollard, (Ed.), Perspect. in Virol., Vol. 5, Acad. Press, New York, pp. 147–166.Google Scholar
  22. 22).
    Hearing, P. and T. Shenk, (1983). Cell 33: 695–703.PubMedCrossRefGoogle Scholar
  23. 23).
    Berk, A.J., F. Lee, T. Harrison, J. Williams and P.A. Sharp. (1979) Cell 17: 935–944.PubMedCrossRefGoogle Scholar
  24. 24).
    Jones, N. and T. Shenk. (1979). Proc. Natl. Acad. Sci. USA 76: 3665–3669.PubMedCrossRefGoogle Scholar
  25. 25).
    Berget, S.M., C. Moore and P.A. Sharp. (1977). Proc. Natl. Acad. Sci. USA 74: 3171.PubMedCrossRefGoogle Scholar
  26. 26).
    Chow, L.T., R.E. Gelinas, T.R. Broker and R.J. Roberts. (1977). Cell 12: 1.PubMedCrossRefGoogle Scholar
  27. 27).
    Pilder, S., M. Moore, J. Logan and T. Shenk. (1986). Mol. Cell. Biol. 6: 470–476.PubMedGoogle Scholar
  28. 28).
    Kitajewski, J., R.J. Schneider, B. Safer, S. Munemitsu, C. Samuels, B. Thimmappaya and T. Shenk. (1986). Cell 45: 195–200.PubMedCrossRefGoogle Scholar
  29. 29).
    Siekierka, J., T.M. Mariano, P.A. Reichel, and M.B. Mathews, (1985), Proc. Natl. Acad. Sci. USA 82: 1959–1963.PubMedCrossRefGoogle Scholar
  30. 30).
    Challberg, M.D. and T.J. Kelly. (1979). Proc. Natl. Acad. Sci. USA 76: 655–659.PubMedCrossRefGoogle Scholar
  31. 31).
    Schrier, P.T., R. Bernards, R.T. Vaessen, A. Houweling, A.J. vander Eb, (1983). Nature (London) 305: 771–775.CrossRefGoogle Scholar
  32. 32).
    Burgert, H.G. and S. Kvist, (1985). Cell 41: 987–997.PubMedCrossRefGoogle Scholar
  33. 33).
    Trentin, J.J., Y. Yabe, and G. Taylor (1962). Science 137: 835–841.PubMedCrossRefGoogle Scholar
  34. 34).
    Hearing, P. and T. Shenk, (1983). Cell 33: 695–703.PubMedCrossRefGoogle Scholar
  35. 35).
    Hearing, P. and T. Shenk. (1986). Cell 45: 229–236.PubMedCrossRefGoogle Scholar
  36. 36).
    Harter, N. and J. Lewis (1978). J. Virol. 26: 736–744.PubMedGoogle Scholar
  37. 37).
    Levine, A.J., (1984). in Curr. Topic. Microbiol. Imm., Ed. W. Doerfler, Vol. 110, Springer-Verlag, New York, pp 143–161.Google Scholar
  38. 38).
    Nevins, J., (1981). Cell 26: 213–220.PubMedCrossRefGoogle Scholar
  39. 39).
    Osborne, T.F., D.N. Avidson, E.S. Tyau, M. Dunsworth-Brown and A.J. Berk (1984). Mol. Cell. Biol. 4: 1293–1305.PubMedGoogle Scholar
  40. 40).
    Hearing, P. and T. Shenk (1985). Mol. Cell. Biol. 5: 3214–3221.PubMedGoogle Scholar
  41. 41).
    Stein, R. and E.B. Ziff. (1984). Mol. Cell. Biol. 4: 2792–2801.PubMedGoogle Scholar
  42. 42).
    Treisman, R., M.R. Green and T. Maniatis (1983). Proc. Natl. Acad. Sci. USA 80: 7428–7432.PubMedCrossRefGoogle Scholar
  43. 43).
    Borrelli, E., R. Hen and P. Chambon (1984) Nature (London) 312: 608–612.CrossRefGoogle Scholar
  44. 44).
    Velcich, A. and E. Ziff (1985). Cell 40: 705–716.PubMedCrossRefGoogle Scholar
  45. 45).
    Bernards, R., A. Howveling, P.I. Schrier, J.L. Bos and A.J. vander Eb, (1982). Virology 120: 422–432.PubMedCrossRefGoogle Scholar
  46. 46).
    Shenk, T. and J. Williams (1984). Curr. Topic. Microbiol. Imm., Vol. 111. Ed. W. Doerfler, Springer-Verlag, New York, pp. 1–30.Google Scholar
  47. 47).
    Chinnadurai, G., (1984) Cancer Cells, Vol. 2, Eds. G. vande Wounde, A.J. Levine, W.C. Topp and J.D. Watson, Cold Spring Harbor Press, New York, pp. 511–517.Google Scholar
  48. 48).
    Logan, J. Pilder S. and T. Shenk. (1984). Cancer Cells, vol. 2, Eds. G. vande Woude, A.J. Levine, W.C. Topp and J.D. Watson, Cold Spring Harbor Press, New York, pp. 527–532.Google Scholar
  49. 49).
    Sarnow, P., P. Hearing, C. Anderson, D. Halbert, T. Shenk and A.J. Levine, (1984). J. Virol. 49: 672–700.Google Scholar
  50. 50).
    Beltz, J. and J. Flint. (1979). J. Mol. Biol. 131: 353–373.PubMedCrossRefGoogle Scholar
  51. 51).
    Friefeld, B.R., J.H. Lichey, J. Field, R.M. Gronostajski, R.A. Guggenheimer, M.D. Krevolin, K. Nagata, J. Hurwitz and M.S. Horwitz, (1984). Curr. Topic. Microbiol. Imm. vol. 110, Ed. W. Doerfler, Springer-Verlag, New York, pp. 221–255.Google Scholar
  52. 52).
    Stillman, B.W. J.B. Lewis, L.T. Chow, M.B. Mathew, J.E. Smart (1981). Cell 23: 497.PubMedCrossRefGoogle Scholar
  53. 53).
    Stillman, B.W. (1981). J. Virol. 37: 139.PubMedGoogle Scholar
  54. 54).
    Flint, J. (1982). Biochem. Biophys. Acta. 651: 175–208.PubMedGoogle Scholar
  55. 55).
    Ross, S.R. and A.J. Levine (1979). Virology 99: 427–430.PubMedCrossRefGoogle Scholar
  56. 56).
    Persson, H., S. Kvist, L. Ostberg, P.A. Petersson and L. Philipson (1979). Cold Spring Harbor Symp. Quant. Biol. 44: 509–517.CrossRefGoogle Scholar
  57. 57).
    Zinkernagel, R.M. and P.C. Doherty. (1979). Adv. Immunol. 27: 51–177.PubMedCrossRefGoogle Scholar
  58. 58).
    Sarnow, P., P. Hearing, C.W. Anderson, N. Reich, A.J. Levine (1982). J. Mol. Biol. 162: 565–583.PubMedCrossRefGoogle Scholar
  59. 59).
    Halbert, D.N., J.R. Cutt and T. Shenk. (1985). J. Virol. 56: 250–257.PubMedGoogle Scholar
  60. 60).
    Ziff, E. and R. Evans. (1978). Cell 15: 1463–1475.PubMedCrossRefGoogle Scholar
  61. 61).
    Fraser, N.W., J.R. Nevins, E. Ziff and J.R. Darnell (1979). J. Mol. Biol. 129: 643–656.PubMedCrossRefGoogle Scholar
  62. 62).
    Hammarskjold, M.L. and G. Wenberg. (1980). Cell 20: 787–795.PubMedCrossRefGoogle Scholar
  63. 63).
    Fowlkes, D. and T. Shenk. (1980). Cell 22: 405–413.PubMedCrossRefGoogle Scholar
  64. 64).
    Guilfoyle, R. and R. Weinmann (1981). Proc. Natl. Acad. Sci. 78: 3378–3382.PubMedCrossRefGoogle Scholar
  65. 65).
    Graham, F.L., P.J. Abraham, C. Mulder, H.L. Hajneker, S.O. Warner, F.A.J. de Vries, W. Fiers and A.J. vander Eb (1974). Cold Spring Harbor Symp. Quant. Biol. 39: 637–650.CrossRefGoogle Scholar
  66. 66).
    Houweling, A., P.J. vanden Eisen, A.J. vander Eb. (1980). Virology 105: 537–550.PubMedCrossRefGoogle Scholar
  67. 67).
    Senear, A.W. and J.B. Lewis. (1986). Mol. Cell. Biol. 6: 1253–1260.PubMedGoogle Scholar
  68. 68).
    Sambrook, J., M. Botchchan, P. Gallimore, B. Ozanne, U. Peterson, J. Williams, P. Sharp (1974). Cold Spring Harbor Symp. Quant. Biol. 39: 615–632.CrossRefGoogle Scholar
  69. 69).
    Logan, J., J.C. Nicolas, W.C. Topp, M. Girard, T. Shenk, A.J. Levine (1981). Virology 115: 419–422.PubMedCrossRefGoogle Scholar
  70. 70).
    Nevins, J.R., M.J. Imperiale, H.T. Kao and L.T. Feldman (1984). Cancer Cells, vol. II, Eds. G. vande Woude, A.J. Levine, W.C. Topp and J.D. Watson, Cold Spring Harbor Press, New York pp. 533–537.Google Scholar
  71. 71).
    Pinhasi-Kimhi, O., D. Michalovity, A. Ben-Zeev and M. Oren. (1986). Nature (London) 320: 182–185.CrossRefGoogle Scholar
  72. 72).
    Sarnow, P., Y.S. Ho, J. Williams and A.J. Levine (1982). Cell 28: 387–394.PubMedCrossRefGoogle Scholar
  73. 73).
    Ehiyahu, D., A. Raz, P. Gruss, D. Givol, M. Oren. (1984). Nature (London) 312: 646–649.CrossRefGoogle Scholar
  74. 74).
    Parada, L.F., H. Land, R.A. Weinberg, D. Wolf and V. Rotter (1984). Nature (London) 312: 649–651.CrossRefGoogle Scholar
  75. 75).
    Jenkins, J.R., K. Rudge, and G.A. Curde. (1984). Nature (London) 312: 651–654.CrossRefGoogle Scholar
  76. 76).
    Eliyahu, D., D. Michalovitz and M. Oren. (1985). Nature (London) 316.: 158–160.PubMedCrossRefGoogle Scholar
  77. 77).
    Kelekar, A. and M.D. Cole. (1986). Mol. Cell. Biol. 6: 7–14.PubMedGoogle Scholar
  78. 78).
    Wolf, D., Harris, N. and V. Rotter (1984). Cell 38: 119–126.PubMedCrossRefGoogle Scholar
  79. 79).
    Kaczmarek, L., M. Oren and R. Baserga (1986). Expt. Cell. Res. 162: 268–272.CrossRefGoogle Scholar
  80. 80).
    Mercer, W.E., C. Avignolo and R. Baserga (1984). Mol. Cell. Biol. 4: 276–281.PubMedGoogle Scholar
  81. 81).
    Milner, J. (1984). Nature (London) 310: 143–145.CrossRefGoogle Scholar
  82. 82).
    Reich, N. and A.J. Levine. (1984). Nature (London) 308: 199–201.CrossRefGoogle Scholar
  83. 83).
    Oren, M., W. Maltzman and A.J. Levine. (1981). Mol. Cell. Biol. 1: 101–110.PubMedGoogle Scholar
  84. 84).
    Linzer, D.J.H. and A.J. Levine. (1979). Cell 17: 43–52.PubMedCrossRefGoogle Scholar
  85. 85).
    Van der Eb, A.J., R. Bernards, P.I. Schrier, J.L. Bos, R.T.M.J. Vaesen, A.G. Jochemsen and C.J.M. Melief (1984). Cancer Cells, vol II, Eds. G. Vande Woude, A.J. Levine, W.C. Topp and J.D. Watson, Cold Spring Harbor Press, New York, pp. 501–510.Google Scholar
  86. 86).
    Norby, E. (1969) J. Gen. Virol, 5, 221CrossRefGoogle Scholar
  87. 87).
    Ziff, E. B. (1980), Nature (London), 287, 491–499CrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1987

Authors and Affiliations

  • Arnold J. Levine
    • 1
  1. 1.Department of Molecular Biology, Lewis Thomas LaboratoryPrinceton UniversityPrincetonUSA

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