Advertisement

The Biology of the Papillomaviruses

  • Peter M. Howley
Part of the NATO ASI Series book series (NSSA, volume 136)

Abstract

The papillomaviruses are grouped together with the polyomaviruses to form the papovavirus family (1). Each of these genera are physically distinguishable by capsid size (55 nanometers versus 40 nanometers) and by the size of their double-stranded DNA genomes (8000 bp versus 5000 bp). The biology of the polyomaviruses which includes SV40 and the human polyomaviruses BK and JC have been well-characterized because they are generally easily replicated in tissue culture. Because of the lack of a tissue culture system to propagate the papillomaviruses, they remained relatively refractory to study until the late 1970s when recombinant DNA technology permitted the cloning of the genomes of individual papillomaviruses which then permitted a systematic study of this group of viruses.

Keywords

Plasmid Replication Squamous Epithelial Cell Condyloma Acuminata Long Control Region Epidermodysplasia Verruciformis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1).
    Melnick J.L. (1962) Science 135, 1128–1130.PubMedGoogle Scholar
  2. 2).
    Ciuffo G. (1907) Giorn Ital Mal Venereol 48, 12–17.Google Scholar
  3. 3).
    Shope R.E. (1933) J. Exp Med 58, 607–624.PubMedGoogle Scholar
  4. 4).
    Rous P., Beard J.W. (1935) J. Exp Med 62, 523–548.PubMedGoogle Scholar
  5. 5).
    Jenson A.B., Rosenthal J.D., Olson C., Pass F., Lancaster W.D., Shah K (1980) JNCI 64, 495–500.PubMedGoogle Scholar
  6. 6).
    Favre M., Orth G., Croissant O., Yaniv M. (1975) Proc Natl Acad Sci USA 72, 4810–4814.PubMedGoogle Scholar
  7. 7).
    Gissmann L., zur Hausen H. (1976) Proc Natl Acad Sci USA 73, 1310–1313.PubMedGoogle Scholar
  8. 8).
    Law M.-F., Lancaster W.D., Howley P.M. (1979) J. Virol 32, 199–207.PubMedGoogle Scholar
  9. 9).
    Heilman CA., Law M.-F., Israel M.A., Howley P.M. (1980) J. Virol 35, 395–407.Google Scholar
  10. 10).
    Howley P.M., Israel M.A., Law M.-F., Martin M.A. (1979) J. Biol Chem 254, 4876–4883.PubMedGoogle Scholar
  11. 11).
    Kryzek R.A., Watts S.L., Anderson D.L., Faras A.J., Pass F. (1980) J. Virol 36, 236–244.Google Scholar
  12. 12).
    Lancaster W.D., Jenson A.B. (1981) Intervirology 15, 204–212.PubMedGoogle Scholar
  13. 13).
    Durst M., Gissmann L., Ikenberg K., zur Hausen H. (1983) Proc Natl Acad Sci USA 80, 3812–3815.PubMedGoogle Scholar
  14. 14).
    Boshart M., Gissmann L., Ikenberg H., Zur Hausen H. (1984) EMBO J. 3, 1151–1157.PubMedGoogle Scholar
  15. 15).
    Coggin J.R., zur Hausen H. (1979) Cancer Res 39, 545–546.Google Scholar
  16. 16).
    Orth G., Favre M., Croissant O. (1977) J. Virol 24, 108–120.PubMedGoogle Scholar
  17. 17).
    Orth G., Jablonska S., Favre M., Croissant O., Jarzabek-Chorzelska M., Rzesa G. (1978) Proc Natl Acad Sci USA 75, 1537–1541.PubMedGoogle Scholar
  18. 18).
    Gissmann N.L., Pfister H., zur Hausen H. (1977) Virology 7, 569–580.Google Scholar
  19. 19).
    Orth G., Favre M., Breitburd F., Croissant O., Jablonska S., Obalek S., Jarzabek-Chorzelska M., Rzesa G. (1980) Cold Spring Harbor Conference on Cell Proliferation 7, 259–282.Google Scholar
  20. 20).
    Gissmann L., zur Hausen H. (1980) Int J. Cancer 25, 605–609.PubMedGoogle Scholar
  21. 21).
    Ostrow R.S., Kryzyek R., Pass F., Faras A.J. (1981) Virology 108, 21–27.PubMedGoogle Scholar
  22. 22).
    Orth G., Jablonska S., Favre M., Croissant O., Jarzabek-Chorzelska M., Jibard N. (1981) J. Invest Derm 76, 97–102.PubMedGoogle Scholar
  23. 23).
    Pfister H., Nurnberg F., Gissmann L., zur Hausen H. (1981) Int J. Cancer 27, 645–650.PubMedGoogle Scholar
  24. 24).
    Kremsdorf D., Jablonska S., Favre M., Orth G. (1982) J. Virol 43, 436–447.PubMedGoogle Scholar
  25. 25).
    Kremsdorf D., Jablonska S., Favre M., Orth G. (1983) J. Virol 48, 340–351.PubMedGoogle Scholar
  26. 26).
    Gissmann L., Diehl V., Schultz-Coulon H., zur Hausen H. (1982) J. Virol 44, 393–400.PubMedGoogle Scholar
  27. 27).
    Pfister H., Hettich I., Runne U., Gissmann L., Chilf G.N. (1983) J. Virol 47, 363–366.PubMedGoogle Scholar
  28. 28).
    Tsumori T., Yutsudo M., Nakano Y., Tanigaki T., Kitamura H., Hakura A. (1983) J. Gen Virol 64, 967–969.PubMedGoogle Scholar
  29. 29).
    Kremsdorf D., Favre M., Jablonska S., Obalek S., Rueda L.A., Lutzner M., Blanchet-Bardon C., van Voorst Vader P.C., Orth G. (1984) J. Virol 52, 1013–1018.PubMedGoogle Scholar
  30. 30).
    Gassenmaier A., Lammel M., Pfister H. (1984) J. Virol 52, 1019–1023.PubMedGoogle Scholar
  31. 31).
    Ostrow Rs, Zachow K.R., Thompson O., Far as A.J. (1984) J. Invest Dermatol 82, 362–366.PubMedGoogle Scholar
  32. 32).
    Kahn T., Schwarz E., zur Hausen H. (1986) Int J. Cancer (in press).Google Scholar
  33. 33).
    Lorincz A.T., Lancaster W.D., Temple G.F. (1986) J. Virol 58, 225–229.PubMedGoogle Scholar
  34. 34).
    Beaudenon S., Kremsdorf D., Croissant O., Jablonska S., Wain-Hobson S., Orth G. (1986) Nature (London) 321, 246–249.Google Scholar
  35. 35).
    Howley P.M., & Schlegel R. (1987) In: The Papillomaviruses P.M. Howley, N. Salzman, eds., Plenum Press, New York (in press).Google Scholar
  36. 36).
    Black P.H., Hartley J.W., Rowe W.P., Huebner R.J. (1963) Nature (London) 199, 1016–1018.Google Scholar
  37. 37).
    Thomas M., Boiron M., Tanzer J., Levy J.P., Bernard J. (1964) Nature (London) 202, 709–710.Google Scholar
  38. 38).
    Boiron M., Levy J.P., Thomas M., Friedman J.C., Bernard J. (1964) Nature (London) 201, 423–424.Google Scholar
  39. 39).
    Dvoretzky I., Shober R., Lowy D.R. (1980) Virology 103, 369–375.PubMedGoogle Scholar
  40. 40).
    Law M.-F., Lowy D. R,. Dvoretzky I., Howley P. M. (1981) Proc Natl Acad Sci USA 78, 2727–2731.PubMedGoogle Scholar
  41. 41).
    Sarver N., Gruss P., Law M.F., Khoury G., Howley P.M. (1981) Mol Cell Biol 1, 486–496.PubMedGoogle Scholar
  42. 42).
    Sarver N., Byrne J.C., Howley P.M. (1982) Proc Natl Acad Sci USA 79, 7147–7151.PubMedGoogle Scholar
  43. 43).
    DiMaio D., Metherall J., Neary K., Guralski D. (1985). In: Papillomaviruses P. Howley, T. Broker, eds., Alan R. Liss, New York, 437–456.Google Scholar
  44. 44).
    Sarver N., Muschel R., Byrne J.C., Khoury G., Howley P.M. (1985) Mol Cell Biol 5, 3507–3516.PubMedGoogle Scholar
  45. 45).
    Allshire R.C., Bostock C.J. (1986) J. Mol Biol 188, 1–13.PubMedGoogle Scholar
  46. 46).
    Turek L.P., Byrne J.C., Lowy D.R., Dvoretzky I., Friedman R.M., Howley P.M. (1982) Proc Natl Acad Sci USA 79, 7914–7918.PubMedGoogle Scholar
  47. 47).
    Danos O., Katinka M., Yaniv M. (1982) EMBO J. 1, 231–236.PubMedGoogle Scholar
  48. 48).
    Schwarz E., Durst M., Demankowski C., Lattermann O., Zech R., Wolfsperger L., Suhai S., zur Hausen H. (1983) EMBO J. 2, 2341–2348.PubMedGoogle Scholar
  49. 49).
    Fuchs P.G., Iftner T., Weninger J., Pfister H. (1986) J. Virol 58, 626–634.PubMedGoogle Scholar
  50. 50).
    Dartmann K., Schwarz E., Gissmann L., zur Hausen H. (1986) Virology 151, 124–130.PubMedGoogle Scholar
  51. 51).
    Seedorf K., Krammer G., Durst M., Suhai S., Rowekamp W.G. (1985) Virology 145, 181–185.PubMedGoogle Scholar
  52. 52).
    Cole S.T., Streeck R.E. (1986) J. Virol 58, 991–995.PubMedGoogle Scholar
  53. 53).
    Chen E.Y., Howley P.M., Levenson A.D., Seeburg P.H. (1982) Nature (London) 299, 529–534.Google Scholar
  54. 54).
    Giri I., Danos O., Yaniv M. (1985) Proc Natl Acad Sci USA 82, 1580–1584.PubMedGoogle Scholar
  55. 55).
    Groff D.E., Lancaster W.D. (1985) J. Virol 56, 85–91.PubMedGoogle Scholar
  56. 56).
    Heilman C.A., Engel L., Lowy D.R., Howley P.M. (1982) Virology 119, 22–34.PubMedGoogle Scholar
  57. 57).
    Engel L.W., Heilman C.A., Howley P.M. (1983) J. Virol 47, 516–528.PubMedGoogle Scholar
  58. 58).
    Georges E., Croissant O., Bonneaud N., Orth G. (1984) J. Virol 51, 530–538.PubMedGoogle Scholar
  59. 59).
    Schneider-Gadicke A., Schwarz E. (1986) EMBO J. 5, 2285–2292.PubMedGoogle Scholar
  60. 60).
    Sarver N., Rabson M.S., Yang Y.-C., Byrne J.C., Howley P.M. (1984) J. Virol 52, 377–388.PubMedGoogle Scholar
  61. 61).
    Lowy D.R., Dvoretzky I., Shober R., Law M.-F., Engel L., Howley P.M. (1980). Nature (London) 287, 72–74.Google Scholar
  62. 62).
    Baker C.C., Howley P.M. (1986) Submitted).Google Scholar
  63. 63).
    Waldeck W., Rosl F., Zentgraf H. (1984) EMBO J. 3, 2173–2178.PubMedGoogle Scholar
  64. 64).
    Stenlund A., Zabielski J., Ahola H., Moreno-Lopez J., Pettersson U. (1985) J. Mol Cell 182, 541–554.Google Scholar
  65. 65).
    Yang Y.-C., Okayama H., Howley P.M. (1985) Proc Natl Acad Sci USA 82, 1030–1034.PubMedGoogle Scholar
  66. 66).
    Roberts J.M., Weintraub H. (1986) Cell 46, 741–752.PubMedGoogle Scholar
  67. 67).
    Berg L., Lusky M., Stenlund A., Botchan M. (1986) Cell 46, 753–762.PubMedGoogle Scholar
  68. 68).
    Lusky M., Botchan M.R. (1985) J. Virol 53, 955–965.PubMedGoogle Scholar
  69. 69).
    Spalholz B.A., Yang Y.-C., Howley P.M. (1985) Cell 42, 183–191.PubMedGoogle Scholar
  70. 70).
    DiMaio D. (1986) J. Virol 57, 475–480.PubMedGoogle Scholar
  71. 71).
    Groff D.E., Lancaster W.D. (1986) Virology 150, 221–230.PubMedGoogle Scholar
  72. 72).
    Rabson MS, Yee C., Yang Y.-C., Howley P.M. (1986) J. Virol 60, 626–634.PubMedGoogle Scholar
  73. 73).
    Doorbar J., Campbell D., Grand R.J.A., Gallimore P.H. (1986) EMBO J. 5, 355–362.PubMedGoogle Scholar
  74. 74).
    Yang Y.-C., Spalholz B.A., Rabson M.S., Howley P.M. (1985) Nature (London) 318, 575–577.Google Scholar
  75. 75).
    DiMaio D., Guralski D., Schiller J.T. (1986) Proc Natl Acad Sci USA 83, 1797–1801.PubMedGoogle Scholar
  76. 76).
    Schiller J.T., Vass W.C., Lowy D.R. (1984) Proc Natl Acad Sci USA 81, 7880–7884.PubMedGoogle Scholar
  77. 77).
    Berg L.J., Singh K., Botchan M. (1986) Mol Cell Biol 6, 859–869.PubMedGoogle Scholar
  78. 78).
    Pilacinski W.P., Glassman D.L., Kryzek R.A., Sadowski P.L., Robbins A.K. (1984) Biotechnology, 2, 356–360.Google Scholar
  79. 79).
    Komly C.A., Breitburd F., Croissant O. and Streeck R.E. (1986) J. Virol (in press).Google Scholar
  80. 80).
    Ahola H., Stenlund A., Moreno-Lopez J., Pettersson U. (1983) Nucleic Acids Res 11, 2639–2650.PubMedGoogle Scholar
  81. 81).
    Pettersson U., Ahola H., Stenlund A., Bergman P., Ustav M., Moreno-Lopez J. (1986). In: Papillomaviruses D. Evered, S. Clark, eds., John Wiley and Sons, Chichester, 23–34.Google Scholar
  82. 82).
    Amtmann E., Sauer G. (1982) J. Virol 43, 59–66.PubMedGoogle Scholar
  83. 83).
    Lusky M., Berg L., Weiher H., Botchan M. (1983) Mol Cell Biol 3, 1108–1122.PubMedGoogle Scholar
  84. 84).
    Campo M.S., Spandidos D.A., Lang J., Wilkie N.M. (1983) Nature (London) 303, 77–80.Google Scholar
  85. 85).
    Weiher H., Botchan M.R. (1984) Nucleic Acids Res 12, 2901–2916.PubMedGoogle Scholar
  86. 86).
    Howley P.M., Schenbron E.T., Lund E., Byrne J.C., Dahlberg J.E. (1985) Mol Cell Biol 5, 3310–3315.PubMedGoogle Scholar
  87. 87).
    Lancaster W.D., Olson C. (1982) Microbiol. Reviews 46, 191–207.Google Scholar
  88. 88).
    Howley P.M. (1985) Amer J. Path 113, 414–421.Google Scholar
  89. 89).
    Lancaster W.D. (1981) Virology 108, 251–255.PubMedGoogle Scholar
  90. 90).
    Binetruy B., Meneguzzi G., Breatnach R., Cuzin F. (1982) EMBO J. 1, 621–628.PubMedGoogle Scholar
  91. 91).
    Babiss L.E., Fisher P.B. (1986) Virology 154, 180–194.PubMedGoogle Scholar
  92. 92).
    Botchan M., Berg L., Reynolds J., Lusky M. (1986). In: Papillomaviruses, D. Evered, S. Clark, eds., John Wiley and Sons, Chichester, 53–63.Google Scholar
  93. 93).
    Lusky M., Botchan M.R. (1984) Cell 36, 391–401.PubMedGoogle Scholar
  94. 94).
    Lusky M., Botchan M.R. (1986) Proc Natl Acad Sci USA 83, 3609–3613.PubMedGoogle Scholar
  95. 95).
    Nakabayashi Y., Chattopadhyay S.K., Lowy D.R. (1983) Proc Natl Acad Sci USA 80, 5832–5836.PubMedGoogle Scholar
  96. 96).
    Schiller J., Vousden K., Vass W.C., Lowy D.R. (1986) J. Virol 57, 1–6.PubMedGoogle Scholar
  97. 97).
    Androphy E.J., Schiller J.T., Lowy D.R. (1985) Science 230, 442–445.PubMedGoogle Scholar
  98. 98).
    Nasseri M., Wettstein F.O. (1984) J. Virol 51, 706–712.PubMedGoogle Scholar
  99. 99).
    Danos O., Georges E., Orth G., Yaniv M. (1985) J. Virol 53, 735–741.PubMedGoogle Scholar
  100. 100).
    Baker C.C., Phelps W.C., Lindgren V., Braun M., Gonda M., Howley P.M. (1986) Submitted.Google Scholar
  101. 101).
    Schwarz E., Freese U.K., Gissmann L., Mayer W., Roggenbuck B., Stremlau A., zur Hausen H. (1985) Nature (London) 314, 111–114.Google Scholar
  102. 102).
    Schlegel R., Wade-Glass M., Rabson MS, Yang Y-C (1986) Science 233, 464–466.PubMedGoogle Scholar
  103. 103).
    Rous P., Kidd J.G. (1936) Science 83, 468–469.PubMedGoogle Scholar
  104. 104).
    Kidd J.G., Rous P. (1937) Proc Soc Exp Biol Med 37, 518–520.Google Scholar
  105. 105).
    Rous P., Kidd J.G., Smith W.E. (1953) J. Exp Med 96, 159–174.Google Scholar
  106. 106).
    Ito Y. (1960) Virology 12, 596–601.PubMedGoogle Scholar
  107. 107).
    Stevens J.G., Wettstein F.O. (1979) J. Virol 30, 891–898.PubMedGoogle Scholar
  108. 108).
    Sugawara K., Fujinaga K., Yamashita T., Ito Y. (1983) Virology 131, 88–99.PubMedGoogle Scholar
  109. 109).
    Georges E., Croissant O., Bonneaud N., Orth G. (1984) J. Virol 51, 530–538.PubMedGoogle Scholar
  110. 110).
    Jarrett W.F.H., McNeil P.E., Grimshaw W.I.R., Selman I.E., Mclntyre W.I.M. (1978) Nature (London) 274, 215–217.Google Scholar
  111. 111).
    Campo M.S., Moar M.H., Sartirana M.L., Kennedy I.M., Jarrett, W.F.H. (1985) EMBO J. 4, 1819–1825.PubMedGoogle Scholar
  112. 112).
    Campo M.S., Spandidos D.A. (1983) J. Gen Virol 64, 549–557.PubMedGoogle Scholar
  113. 113).
    Ford J.N., Jennings P.A., Spradbrow P.B., Francis J. (1982) Res Vet Sci 32, 257–259.PubMedGoogle Scholar
  114. 114).
    Vanseow B.A., Spradbrow P.B., Jackson A.R.B. (1982) Vet Record 110, 561–562.Google Scholar
  115. 115).
    Lutzner M. (1978) Bull. Cancer 65, 169–182.PubMedGoogle Scholar
  116. 116).
    Orth G. (1986). In: Papillomaviruses, D. Evered and S. Clark, eds., John Wiley and Sons, Chichester, 157–174.Google Scholar
  117. 117).
    Ostrow R.S., Bender M., Niimura M., Seki T., Kawashima M., Pass F., Faras A.J. (1982) Proc Natl Acad Sci USA 79, 1634–1638.PubMedGoogle Scholar
  118. 118).
    Pfister H., Gassenmaier A. and Nurnberger F. (1983) Cancer Res 43, 1436–1441.PubMedGoogle Scholar
  119. 119).
    Vonka V., Kanda J., Hirsch I., Zavadeva H., Krcmar M., Suchankova A., Rezakova D., Broucek J., Press M., Domorazkova E., Svoboda B., Havrankova A., Jelinek J. (1984) Int J. Cancer 33, 61–66.PubMedGoogle Scholar
  120. 120).
    Vonka V., Kanda J., Jelinek J., Subrt I., Sucharek A., Havrankova A., Vachal M., Hirsch I, Domorazkova E, Zavadova H, Richterova V., Naprstkova J., Dvorakova V., Svoboda B. (1984) Int J. Cancer 33, 49–60.PubMedGoogle Scholar
  121. 121).
    Meisels A., Fortin R. (1976) Acta Cytol 20, 505–509.PubMedGoogle Scholar
  122. 122).
    Purola E., Savia E. (1977) Acta Cytol 21, 26–31.PubMedGoogle Scholar
  123. 123).
    Laverty C.R., Russell P., Hills E., Booth N. (1978) Acta Cytol 22, 195–201.PubMedGoogle Scholar
  124. 124).
    Gissmann L., Wolnik L., Ikenberg H., Koldovsky U., Schnurch G. and zur Hausen H. (1983) Proc Natl Acad Sci USA 80, 560–563.PubMedGoogle Scholar
  125. 125).
    Gissmann L., Schwarz E. (1986). In: Papillomaviruses D. Evered, S. Clark, eds., John Wiley and Sons, Chichester, 190–197.Google Scholar
  126. 126).
    Steinberg B.M., Topp W.C., Schneider P.S., Abramson A.L. (1983) N. Engl J. Med 308, 1261–1264.PubMedGoogle Scholar
  127. 127).
    Ferenczy A., Mitao M., Nagai N., Silverstein S.J., Crum C.P. (1985) N. Engl J. Med 313, 784–788.PubMedGoogle Scholar
  128. 128).
    Macnab J.C.M., Walkinshaw S.A., Cordiner J.W., Clements J.B. (1986) N. Engl J. Med 315, 1052–1058.PubMedGoogle Scholar

Copyright information

© Plenum Press, New York 1987

Authors and Affiliations

  • Peter M. Howley
    • 1
  1. 1.Laboratory of Tumor Virus BiologyNatl. Cancer InstituteBethesdaUSA

Personalised recommendations